C₃₇H₅₇NO₇S

Base Information

• Chemical Name: C₃₇H₅₇NO₇S
• CAS No.: 1422975-19-6
• Molecular Formula: C₃₇H₅₇NO₇S
• Molecular Weight: 659.928
• Mol file: 1422975-19-6.mol

Synonyms:C₃₇H₅₇NO₇S

Chemical Property of C₃₇H₅₇NO₇S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₇H₅₇NO₇S

There total 4 articles about C₃₇H₅₇NO₇S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.0%

C33H39NO3S (1422975-15-2) + C32H44O7 (1422974-98-8) → C37H57NO7S (1422975-14-1) + C37H57NO7S (1422975-19-6)

Guidance literature:

C₃₃H₃₉NO₃S; C₃₂H₄₄O₇; With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 24h;

With triethylsilane; 1,1,1,3',3',3'-hexafluoro-propanol; trifluoroacetic acid; at 20 ℃; for 0.5h;

Reference yield:

C32H44O7 (1422974-98-8) + C33H39NO3S → C37H57NO7S (1422974-99-9) + C37H57NO7S (1422975-14-1) + C37H57NO7S (1422975-17-4) + C37H57NO7S (1422975-19-6)

Guidance literature:

C₃₂H₄₄O₇; C₃₃H₃₉NO₃S; With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 12h;

With triethylsilane; 1,1,1,3',3',3'-hexafluoro-propanol; trifluoroacetic acid; at 20 ℃; for 0.5h; Overall yield = 26 %; Overall yield = 8.1 mg;

Reference yield:

C32H58O5Si3 (84414-22-2) → C37H57NO7S (1422975-19-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane; water / 5 h / 20 °C

2.1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 24 h / 20 °C / Molecular sieve

2.2: 0.5 h / 20 °C

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; water;

upstream raw materials:

C₃₃H₃₉NO₃S

C₃₂H₄₄O₇

treprostinil

C₃₂H₅₈O₅Si₃

Refernces

• 1、 -. "SUSTAINED RELEASE COMPOSITION OF PROSTACYCLIN". Page/Page column 118; 119; 120. . Retrieved 2013/03/26.