Vincetoxicoside B

Base Information

• Chemical Name: Vincetoxicoside B
• CAS No.: 22007-72-3
• Molecular Formula: C21H20 O11
• Molecular Weight: 448.383
• DSSTox Substance ID: DTXSID00944612
• Nikkaji Number: J427.599C
• Wikidata: Q27145708
• ChEMBL ID: CHEMBL4466394
• Mol file: 22007-72-3.mol

Synonyms:quercetin 7-rhamnoside

Chemical Property of Vincetoxicoside B

Chemical Property:

• Vapor Pressure: 4.4E-27mmHg at 25°C
• Melting Point: 174-175℃ (methanol )
• Boiling Point: 801.1°Cat760mmHg
• PKA: 5.92±0.40(Predicted)
• Flash Point: 283.8°C
• PSA: 190.28000
• Density: 1.737g/cm³
• LogP: 0.48870
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 3
• Exact Mass: 448.10056145
• Heavy Atom Count: 32
• Complexity: 741

Purity/Quality:

99.5% ^*data from raw suppliers

Quercetin 7-rhamnoside ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1C(C(C(C(O1)OC2=CC(=C3C(=C2)OC(=C(C3=O)O)C4=CC(=C(C=C4)O)O)O)O)O)O
• Isomeric SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=CC(=C3C(=C2)OC(=C(C3=O)O)C4=CC(=C(C=C4)O)O)O)O)O)O

Technology Process of Vincetoxicoside B

There total 2 articles about Vincetoxicoside B which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

thymidine diphosphate-L-rhamnose (16268-29-4,62012-79-7) + quercetol (117-39-5,74893-81-5) → 7-O-α-L-rhamnopyranoside 4',3,5,7-tetrahydroxyflavone (22007-72-3)

Guidance literature:

With flavonol 7-O-rhamnosyltransferase from Arabidopsis thaliana; In dimethyl sulfoxide; at 20 ℃; for 48h; regiospecific reaction; Microbiological reaction; Enzymatic reaction;

DOI:10.1016/j.carres.2015.09.010

Reference yield:

quercitin-3-O-β-D-glucoside-7-O-α-L-rhamnoside (124097-46-7,18016-58-5,38784-81-5) → D-Glucose (2280-44-6) + 7-O-α-L-rhamnopyranoside 4',3,5,7-tetrahydroxyflavone (22007-72-3)

Guidance literature:

With water; Enzymatic reaction;

DOI:10.1007/s10600-012-0234-0

Reference yield:

7-O-α-L-rhamnopyranoside 4',3,5,7-tetrahydroxyflavone (22007-72-3) → L-rhamnose (73-34-7) + quercetol (117-39-5,74893-81-5)

Guidance literature:

With hydrogenchloride; In methanol; at 80 ℃; for 4h;

DOI:10.3390/molecules26195827

upstream raw materials:

quercitin-3-O-β-D-glucoside-7-O-α-L-rhamnoside

thymidine diphosphate-L-rhamnose

quercetol

Downstream raw materials:

D-quionovose

L-rhamnose

quercetol

Refernces

• 1、 Alaniya,Kavtaradze,Skhirtladze,Sutiashvili,Kemertelidze. "Flavonoid glycosides from flowers of Sisymbrium officinale and Diplotaxis muralis growing in Georgia". body text. p. 315 - 316. Retrieved 2012/09/22.