D₆-1-aminocyclohexanecarboxylic acid

Base Information

• Chemical Name: D₆-1-aminocyclohexanecarboxylic acid
• CAS No.: 1398718-12-1
• Molecular Formula: C₇H₁₃NO₂
• Molecular Weight: 149.138
• Mol file: 1398718-12-1.mol

Synonyms:D₆-1-aminocyclohexanecarboxylic acid

Chemical Property of D₆-1-aminocyclohexanecarboxylic acid

Chemical Property:

Purity/Quality:

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Technology Process of D₆-1-aminocyclohexanecarboxylic acid

There total 2 articles about D₆-1-aminocyclohexanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C8H6(2)H6N2O2 (1398718-14-3) → D6-1-aminocyclohexanecarboxylic acid (1398718-12-1)

Guidance literature:

With ethanol; sodium hydroxide; Reflux;

Reference yield:

3,3,4,4,5,5-hexadeuterio-cyclohexanone (54513-99-4) → D6-1-aminocyclohexanecarboxylic acid (1398718-12-1)

Guidance literature:

Multi-step reaction with 2 steps

1: water / ethanol / 12 h / 50 °C

2: sodium hydroxide; ethanol / Reflux

With ethanol; water; sodium hydroxide; In ethanol;

Reference yield: 16.0%

D6-1-aminocyclohexanecarboxylic acid (1398718-12-1) + N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide (82911-69-1) → D6-1-(((9H-fluoren-9-yl)methoxy)carbonylamino)cyclohexane carboxylic acid (1398718-16-5)

Guidance literature:

D₆-1-aminocyclohexanecarboxylic acid; With hydrogenchloride; In water; pH=10;

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide; In water; acetonitrile; at 20 ℃;

upstream raw materials:

C₈H₆⁽²⁾H₆N₂O₂

3,3,4,4,5,5-hexadeuterio-cyclohexanone

Downstream raw materials:

D₆-1-(((9H-fluoren-9-yl)methoxy)carbonylamino)cyclohexane carboxylic acid

(S)-D₆-1-amino-N-(1-cyano-2-(4'-((4-methyl-piperazin-1-yl)methyl)biphenyl-4-yl)ethyl)cyclohexanecarboxamide

(S)-D₆-(9H-fluoren-9-yl)methyl 1-(1-cyano-2-(4'-((4-methylpiperazin-1-yl)methyl)biphenyl-4-yl)ethylcarbamoyl)cyclohexylcarbamate

Refernces