Technology Process of 5-benzyl-4-(4-methoxyphenyl)-N-(naphthalen-2-ylmethyl)thiazol-2-amine
There total 7 articles about 5-benzyl-4-(4-methoxyphenyl)-N-(naphthalen-2-ylmethyl)thiazol-2-amine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: palladium on activated charcoal; hydrogen / ethyl acetate / 20 °C
2: aluminum (III) chloride; bromine / chloroform / 6 h / 20 °C
3: sodium acetate / ethanol / 80 °C
4: toluene-4-sulfonic acid / toluene / 130 °C
5: sodium tetrahydroborate / ethanol / 20 °C
With
aluminum (III) chloride; sodium tetrahydroborate; palladium on activated charcoal; hydrogen; bromine; sodium acetate; toluene-4-sulfonic acid;
In
ethanol; chloroform; ethyl acetate; toluene;
DOI:10.1016/j.ejmech.2014.07.072
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium hydroxide / ethanol; water / 0.17 h / 20 °C
1.2: 20 °C
2.1: palladium on activated charcoal; hydrogen / ethyl acetate / 20 °C
3.1: aluminum (III) chloride; bromine / chloroform / 6 h / 20 °C
4.1: sodium acetate / ethanol / 80 °C
5.1: toluene-4-sulfonic acid / toluene / 130 °C
6.1: sodium tetrahydroborate / ethanol / 20 °C
With
aluminum (III) chloride; sodium tetrahydroborate; palladium on activated charcoal; hydrogen; bromine; sodium acetate; toluene-4-sulfonic acid; sodium hydroxide;
In
ethanol; chloroform; water; ethyl acetate; toluene;
DOI:10.1016/j.ejmech.2014.07.072