Trospium Chloride Related Compound C (20 mg) (Azoniaspironortropanol chloride)

Base Information

• Chemical Name: Trospium Chloride Related Compound C (20 mg) (Azoniaspironortropanol chloride)
• CAS No.: 3464-71-9
• Molecular Formula: C₁₁H₂₀NO*Cl
• Molecular Weight: 217.739
• Hs Code.: 2933999552
• Mol file: 3464-71-9.mol

Synonyms:Trospium spiroalcohol

Chemical Property of Trospium Chloride Related Compound C (20 mg) (Azoniaspironortropanol chloride)

Chemical Property:

• Melting Point: 294-297℃
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99.9% ^*data from raw suppliers

AzoniaspironortropanolChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Trospium Chloride Related Compound C is an intermediate used for the synthesis of Trospium Chloride (T892800), an Antispasmodic, used in treatment of urinary incontinence.

Technology Process of Trospium Chloride Related Compound C (20 mg) (Azoniaspironortropanol chloride)

There total 1 articles about Trospium Chloride Related Compound C (20 mg) (Azoniaspironortropanol chloride) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,4-dichlorobutane (110-56-5) + nortropine (538-09-0) → Trospium spiroalcohol (3464-71-9)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In N,N-dimethyl-formamide; at 80 ℃; for 2h;

Reference yield: 78.0%

Trospium spiroalcohol (3464-71-9) + Benzilic acid imidazolide (15441-11-9) → trospium chloride (10405-02-4)

Guidance literature:

dmap; In N,N-dimethyl-formamide; at 80 ℃; for 1.08333h; Product distribution / selectivity;

upstream raw materials:

1,4-dichlorobutane

nortropine

Downstream raw materials:

trospium chloride

Refernces