CHONDROITINASE ABC

Base Information

• Chemical Name: CHONDROITINASE ABC
• CAS No.: 9024-13-9
• Molecular Formula: NULL
• Molecular Weight: 0
• Mol file: 9024-13-9.mol

Synonyms:ChondroitinABC eliminase; Chondroitin ABC endolyase; Chondroitin sulfate ABC lyase;Chondroitin sulfate depolymerase; Chondroitinase; Chondroitinase ABC;Condoliase; E.C. 4.2.2.20; E.C. 4.2.2.4; EC 4.2.2.20

Chemical Property of CHONDROITINASE ABC

Chemical Property:

• Storage Temp.: −20°C
• Solubility.: 0.01% bovine serum albumin aqueous (BSA) solution: soluble

Purity/Quality:

98%,99%, ^*data from raw suppliers

Chondroitinase?ABC from Proteus vulgaris BSA free, lyophilized powder, specific activity 50-250 units/mg protein ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

Useful:

• Uses: Chondroitinase ABC from Sigma has been used to digest O-linked chondroitin sulfate-like glycosaminoglycan (CSGAG). The enzyme has also been used to digest glycosaminoglycan chains in proteoglycans during the construction and expression of a recombinant versican gene in mammalian systems. Furthermore, it has been used to digest chondroitin sulfate in the proteoglycan complexes. The enzyme has also been used in the removal of glycan chains from aggrecan, which eliminates the axon growth-inhibitory effect of aggrecan. The enzyme has been used to study the consequences of inducing acute, long-lasting changes in chondroitin sulfate proteoglycans using adult rat brain cells. Glycosaminoglycans have been digested with chondroitinase ABC for chondroitin/dermatan sulfate quantitation in keratocyte cell cultures obtained from fresh bovine corneal stromae.