3-Anilino-4-(2-hydroperoxy-prop-2-yl)-5-hydroxy-1-phenyl-pyrazol

Base Information

• Chemical Name: 3-Anilino-4-(2-hydroperoxy-prop-2-yl)-5-hydroxy-1-phenyl-pyrazol
• CAS No.: 99367-86-9
• Molecular Formula: C₁₈H₁₉N₃O₃
• Molecular Weight: 325.367
• Mol file: 99367-86-9.mol

Synonyms:3-Anilino-4-(2-hydroperoxy-prop-2-yl)-5-hydroxy-1-phenyl-pyrazol

Chemical Property of 3-Anilino-4-(2-hydroperoxy-prop-2-yl)-5-hydroxy-1-phenyl-pyrazol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 3-Anilino-4-(2-hydroperoxy-prop-2-yl)-5-hydroxy-1-phenyl-pyrazol

There total 2 articles about 3-Anilino-4-(2-hydroperoxy-prop-2-yl)-5-hydroxy-1-phenyl-pyrazol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

3-Anilino-4-isopropyliden-1-phenyl-pyrazolin-5-on (99367-75-6) → 3-Anilino-4-(2-hydroperoxy-prop-2-yl)-5-hydroxy-1-phenyl-pyrazol (99367-86-9)

Guidance literature:

With sulfuric acid; dihydrogen peroxide; In diethyl ether; at 0 - 5 ℃; for 6h;

Reference yield:

5-anilino-2,4-dihydro-2-phenyl-3H-pyrazole-3-one (7186-66-5) → 3-Anilino-4-(2-hydroperoxy-prop-2-yl)-5-hydroxy-1-phenyl-pyrazol (99367-86-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 41 percent / AcOH / Ambient temperature

2: 42 percent / 20-30percent H₂O₂, conc. H₂SO₄ / diethyl ether / 6 h / 0 - 5 °C

With sulfuric acid; dihydrogen peroxide; acetic acid; In diethyl ether;

Reference yield:

3-Anilino-4-(2-hydroperoxy-prop-2-yl)-5-hydroxy-1-phenyl-pyrazol (99367-86-9) → 2,2-Dimethyl-5-phenyl-7-phenylamino-1-oxa-5,6-diaza-spiro[2.4]hept-6-en-4-one (99367-82-5)

Guidance literature:

With sodium hydroxide; In methanol; Yield given; Ambient temperature;

upstream raw materials:

3-Anilino-4-isopropyliden-1-phenyl-pyrazolin-5-on

5-anilino-2,4-dihydro-2-phenyl-3H-pyrazole-3-one

Downstream raw materials:

2,2-Dimethyl-5-phenyl-7-phenylamino-1-oxa-5,6-diaza-spiro[2.4]hept-6-en-4-one

Refernces