Lactose monohydrate

Base Information

• Chemical Name: Lactose monohydrate
• CAS No.: 5989-81-1
• Deprecated CAS: 10039-26-6,96231-95-7
• Molecular Formula: C12H24O12
• Molecular Weight: 360.315
• Hs Code.: 17021100
• European Community (EC) Number: 600-087-0,611-913-4,613-418-9
• UNII: EWQ57Q8I5X
• DSSTox Substance ID: DTXSID1052828
• Wikidata: Q27277391
• NCI Thesaurus Code: C76719
• RXCUI: 1305527
• Mol file: 5989-81-1.mol

Synonyms:Lactose monohydrate;5989-81-1;alpha-Lactose monohydrate;alpha-D-Lactose monohydrate;64044-51-5;D-Lactose monohydrate;Respitose;Microtose;Pharmaose;Lactose, monohydrate;Spherolac 100;Lactose(Monohydrate);alpha-lactose hydrate;LACTOSE,MONOHYDRATE;Lactose monohydrate [NF];UNII-EWQ57Q8I5X;EWQ57Q8I5X;(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol;hydrate;Lactose, hydrous;a-D-Glucopyranose, 4-O-b-D-galactopyranosyl-, monohydrate;alpha-D-Glucopyranose, 4-O-beta-D-galactopyranosyl-, monohydrate;4-O-beta-D-Galactopyranosyl-alpha-D-glucose;Lactose monohydrate (NF);10039-26-6;Lactopress;Pharmatose;Lactochem;Lactohale;Wyndale;Wynhale;lactose hydrate;Lactose hydrous;ALPHA-LACTOSEMONOHYDRATE;D-Glucose, 4-O-beta-D-galactopyranosyl-, monohydrate;D-Glucose, 4-O-.beta.-D-galactopyranosyl-, monohydrate;Lactose Monohydrate (Alpha-Form);Pharmatose dcl ii;Supertab 11sd;Supertab 14sd;Supertab 30gr;Supertab 50 odt;Supertab 11sd nz;Pharmatose dcl 11;.alpha.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-, monohydrate;C12-H22-O11.H2-O;Lactopress spray dried;Lactose fastflo 316;(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-{[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}oxane-3,4,5-triol hydrate;(2S,3R,4R,5S,6R)-6-(Hydroxymethyl)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2,3,4-triol hydrate;Alpha-lactose,monohydrate;Lactose (TN);NSC-760401;Lactose (JP17);(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-tetrahydropyran-3,4,5-triol;alpha -lactose monohydrate;SCHEMBL16787;D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-, monohydrate;LACTOSE HYDRATE [JAN];LACTOSE, HYDROUS [II];PHARMATOSE DCL II [II];DTXSID1052828;LACTOSE MONOHYDRATE [II];Lactose, monohydrate, .alpha.-;CHEBI:189432;alpha-Lactose, analytical standard;C12H22O11.H2O;LACTOSE MONOHYDRATE [USP-RS];LACTOSE MONOHYDRATE [WHO-IP];AKOS015896871;FS-3862;NSC 760401;MALONICACIDDISODIUMSALTMONOHYDRATE;(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol hydrate;LACTOSE MONOHYDRATE [EP MONOGRAPH];LS-185374;CS-0128727;LACTOSUM, MONOHYDRATE [WHO-IP LATIN];D03226;E80712;EN300-1608278;alpha-4-O-(beta-D-galactopyranosido)-D-glucopyranose;Q27277391;alpha-Lactose monohydrate, >=99% total lactose basis (GC);4-O-beta-D-Galactopyranosyl-alpha-D-glucopyranose monohydrate;alpha-D-Glucopyranose, 4-O-beta-D-galactopyranosyl-, hydrate;alpha-Lactose monohydrate, BioXtra, >=99% total lactose basis (GC);alpha-Lactose monohydrate, suitable for cell culture, BioReagent;.alpha.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-, hydrate (1:1);66857-12-3

Chemical Property of Lactose monohydrate

Chemical Property:

• Appearance/Colour: White powder
• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 219 °C
• Refractive Index: 1.652
• Boiling Point: 667.9 °C at 760 mmHg
• Flash Point: 357.8 °C
• PSA: 198.76000
• Density: 1,53 g/cm³
• LogP: -5.46150
• Storage Temp.: Store in air tight containers.
• Solubility.: H2O: soluble1M, clear, colorless
• Water Solubility.: Soluble in water.
• Hydrogen Bond Donor Count: 9
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 4
• Exact Mass: 360.12677620
• Heavy Atom Count: 24
• Complexity: 382

Purity/Quality:

98%-102%, ^*data from raw suppliers

a-Lactose monohydrate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 40-36/37/38
• Safety Statements: 24/25-36-26

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Biological Agents -> Disaccharides
• Canonical SMILES: C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)O)CO)O)O)O)O.O
• Isomeric SMILES: C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)O)CO)O)O)O)O.O
• Recent ClinicalTrials: Amantadine for COVID-19
• Recent EU Clinical Trials: A phase II baseline versus treatment study to determine the efficacy of raltegravir (ISENTRESS) in preventing progression of relapsing remitting multiple sclerosis as determined by gadolinium-enhanced MRI
• Uses: alpha-D-Lactose monohydrate is used as a carrier and stabiliser of aromas, pharmaceutical products, Food industry.