ethyl cinnamoyl carbonate

Base Information

• Chemical Name: ethyl cinnamoyl carbonate
• CAS No.: 108761-28-0
• Molecular Formula: C₁₂H₁₂O₄
• Molecular Weight: 220.225
• Mol file: 108761-28-0.mol

Synonyms:ethyl cinnamoyl carbonate

Chemical Property of ethyl cinnamoyl carbonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl cinnamoyl carbonate

There total 6 articles about ethyl cinnamoyl carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chloroformic acid ethyl ester (541-41-3) + Cinnamic acid (621-82-9) → (carbonic acid ethyl ester)-cinnamic acid-anhydride (108761-28-0)

Guidance literature:

With triethylamine; In tetrahydrofuran; at -7 ℃; for 0.5h;

DOI:10.1055/s-1987-28035

Reference yield:

(E)-3-phenylacrylic acid (140-10-3) + chloroformic acid ethyl ester (541-41-3) → ethyl cinnamoyl carbonate (108761-28-0)

Guidance literature:

In dichloromethane;

DOI:10.1016/j.carres.2009.11.009

Reference yield:

potassium cinnamate (63073-96-1) + chloroformic acid ethyl ester (541-41-3) → ethyl cinnamoyl carbonate (108761-28-0)

Guidance literature:

With pyridine; In dichloromethane; at 0 ℃; for 2h;

DOI:10.1002/prac.199533701137

upstream raw materials:

pyridine

(E)-3-phenylacrylic acid

chloroformic acid ethyl ester

Cinnamic acid

Downstream raw materials:

mono-(6-O-cinnamoyl)-β-CD

mono-(2-O-cinnamoyl)-β-CD

cinnamoyl azide

2-hydroxymethyl-1-[2-hydroxy-3-(3-phenylallyloxy)propyl]piperidine-3,4,5-triol

Refernces

• 1、 Bui, Thi Thoi,Tran, Van Loc,Ngo, Dai Quang,Tran, Van Chien,Tran, Van Sung,Tran, Thi Phuong Thao. "Synthesis and evaluation of α-glucosidase inhibitory activity of sulfonylurea derivatives". . p. 163 - 171. Retrieved 2021/03/16.
• 2、 Grigorjeva, Liene,Daugulis, Olafs. "Cobalt-catalyzed, aminoquinoline-directed C(sp2)-H bond alkenylation by alkynes". supporting information. p. 10209 - 10212. Retrieved 2015/03/31.