(2R)-4α-(Dimethylamino)-3,4,5,6,9,11,12,13,14,16-decahydro-3β,5β,8,10,13α-pentahydroxy-6,13-dimethyl-9,16-dioxo-2α,6α-epoxy-2H-naphthaceno[1,2-b]oxocin-14α-carboxylic acid methyl ester

Base Information

• Chemical Name: (2R)-4α-(Dimethylamino)-3,4,5,6,9,11,12,13,14,16-decahydro-3β,5β,8,10,13α-pentahydroxy-6,13-dimethyl-9,16-dioxo-2α,6α-epoxy-2H-naphthaceno[1,2-b]oxocin-14α-carboxylic acid methyl ester
• CAS No.: 62422-00-8
• Molecular Formula: C29H31NO11
• Molecular Weight: 569.61
• Mol file: 62422-00-8.mol

Synonyms:7-Desoxynogalarol;2,6-Epoxy-2H-naphthaceno(1,2-b)oxocin-14-carboxylic acid,3,4,5,6,9,11,12,13,14,16-decahydro-4-(dimethylamino)-3,5,8,10,13-pentahydroxy-6,13-dimethyl-9,16-dioxo-,methyl ester;DEOXYNOGALAROL,7;

Chemical Property of (2R)-4α-(Dimethylamino)-3,4,5,6,9,11,12,13,14,16-decahydro-3β,5β,8,10,13α-pentahydroxy-6,13-dimethyl-9,16-dioxo-2α,6α-epoxy-2H-naphthaceno[1,2-b]oxocin-14α-carboxylic acid methyl ester

Chemical Property:

• Vapor Pressure: 9.28E-31mmHg at 25°C
• Refractive Index: 1.6290 (estimate)
• Boiling Point: 850.3°Cat760mmHg
• Flash Point: 468.1°C
• PSA: 183.29000
• Density: 1.61g/cm³
• LogP: 0.44290

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2R)-4α-(Dimethylamino)-3,4,5,6,9,11,12,13,14,16-decahydro-3β,5β,8,10,13α-pentahydroxy-6,13-dimethyl-9,16-dioxo-2α,6α-epoxy-2H-naphthaceno[1,2-b]oxocin-14α-carboxylic acid methyl ester

There total 2 articles about (2R)-4α-(Dimethylamino)-3,4,5,6,9,11,12,13,14,16-decahydro-3β,5β,8,10,13α-pentahydroxy-6,13-dimethyl-9,16-dioxo-2α,6α-epoxy-2H-naphthaceno[1,2-b]oxocin-14α-carboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 7-Desoxynogalarol (62422-00-8)

Guidance literature:

1, Pd-C, H2;

DOI:10.1021/ja00444a038

Reference yield:

→ 7-Deoxynogalarol (62422-00-8)

Guidance literature:

1, Pd/C - H2;

DOI:10.1021/ja00444a038

Reference yield:

7-deoxynogalarol (62422-00-8) → 7-deoxynogarol (71582-53-1,113532-66-4,116838-50-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.21 g / 0.53 N aq. KOH / 17 h / Ambient temperature

2: 101 mg / dimethylformamide / 65 °C

With potassium hydroxide; In N,N-dimethyl-formamide;

DOI:10.1021/jm00347a016

Downstream raw materials:

7-deoxynogarol