3-chloro-2,4-dihydroxylbenzaldehyde

Base Information

• Chemical Name: 3-chloro-2,4-dihydroxylbenzaldehyde
• CAS No.: 131088-00-1
• Molecular Formula: C₇H₅ClO₃
• Molecular Weight: 172.568
• Mol file: 131088-00-1.mol

Synonyms:3-chloro-2,4-dihydroxylbenzaldehyde

Chemical Property of 3-chloro-2,4-dihydroxylbenzaldehyde

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-chloro-2,4-dihydroxylbenzaldehyde

There total 3 articles about 3-chloro-2,4-dihydroxylbenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,4-Dihydroxybenzaldehyde (95-01-2) → 3-chloro-2,4-dihydroxylbenzaldehyde (131088-00-1)

Guidance literature:

With potassium hydroxide; sodium hypochlorite; In water; at 20 ℃; for 3h;

DOI:10.1021/ol0617291

Reference yield: 65.0%

2,4-Dihydroxybenzaldehyde (95-01-2) → 2,4-dihydroxy-5-chlorobenzaldehyde (131088-02-3) + 3-chloro-2,4-dihydroxylbenzaldehyde (131088-00-1)

Guidance literature:

With piperidine; sodium hypochlorite; sulfuric acid; In water; at 0 - 20 ℃; for 5h;

Reference yield:

malonic acid (141-82-2) + 2,4-Dihydroxybenzaldehyde (95-01-2) → 6-chloro-7-hydroxy-2-oxo-2H-chromene-3-carboxylic acid (183736-74-5) + 3-chloro-2,4-dihydroxylbenzaldehyde (131088-00-1)

Guidance literature:

2,4-Dihydroxybenzaldehyde; With piperidine; sodium hypochlorite; sulfuric acid; In water; at 0 ℃; for 20h; Inert atmosphere;

malonic acid; With pyridine; aniline; at 20 ℃; for 48h; Inert atmosphere;

DOI:10.1021/ma9023679

upstream raw materials:

2,4-Dihydroxybenzaldehyde

malonic acid

Downstream raw materials:

6-bromo-3-chloro-2,4-bis(methoxymethoxy)anisole

6-bromo-3-chloro-2,4-bis(methoxymethoxy)phenol

Refernces

• 1、 -. "SMALL MOLECULE NF-kB INHIBITORS". Paragraph 0137. . Retrieved 2017/07/14.
• 2、 -. "Photodegradable groups for tunable polymeric materials". Page/Page column 17. . Retrieved 2013/02/28.