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Benzarone

Base Information Edit
  • Chemical Name:Benzarone
  • CAS No.:1477-19-6
  • Molecular Formula:C17H14 O3
  • Molecular Weight:266.296
  • Hs Code.:2932999099
  • European Community (EC) Number:216-026-2
  • NSC Number:82134
  • UNII:23ZW4BG89C
  • DSSTox Substance ID:DTXSID2061721
  • Nikkaji Number:J7.747J
  • Wikidata:Q27116149
  • NCI Thesaurus Code:C74411
  • Metabolomics Workbench ID:155640
  • ChEMBL ID:CHEMBL1474963
  • Mol file:1477-19-6.mol
Benzarone

Synonyms:benzaron;benzarone;EHBB

Suppliers and Price of Benzarone
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • Benzarone
  • 25mg
  • $ 65.00
  • TCI Chemical
  • Benzarone
  • 1G
  • $ 38.00
  • TCI Chemical
  • Benzarone
  • 5G
  • $ 186.00
  • Sigma-Aldrich
  • Benzarone European Pharmacopoeia (EP) Reference Standard
  • $ 190.00
  • Sigma-Aldrich
  • Benzarone European Pharmacopoeia (EP) Reference Standard
  • b0490000
  • $ 190.00
  • Sigma-Aldrich
  • Benzarone Aldrich
  • 10mg
  • $ 115.00
  • Medical Isotopes, Inc.
  • Benzarone
  • 10 g
  • $ 1380.00
  • Crysdot
  • (2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone 97%
  • 5g
  • $ 376.00
  • Chem-Impex
  • Benzarone,98%(GC) 98%(GC)
  • 1G
  • $ 107.52
  • Chem-Impex
  • Benzarone,≥98%(GC) ≥98%(GC)
  • 5G
  • $ 425.15
Total 59 raw suppliers
Chemical Property of Benzarone Edit
Chemical Property:
  • Vapor Pressure:1.36E-09mmHg at 25°C 
  • Melting Point:124.3° 
  • Refractive Index:1.5490 (estimate) 
  • Boiling Point:473.6°Cat760mmHg 
  • PKA:7.68±0.15(Predicted) 
  • Flash Point:240.2°C 
  • PSA:50.44000 
  • Density:1.234g/cm3 
  • LogP:3.93180 
  • Storage Temp.:2-8°C 
  • Solubility.:DMSO (Slightly), Methanol (Slightly) 
  • XLogP3:4.3
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:3
  • Exact Mass:266.094294304
  • Heavy Atom Count:20
  • Complexity:346
Purity/Quality:

98%, *data from raw suppliers

Benzarone *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC=C(C=C3)O
  • Uses Benzarone is an EYA (Eyes Absents), multifunctional protein involved in organogenesis, inhibitor which makes it a potent anticancer agent. EYA’s are over expressed in ovarian and breast cancers. As well it is involved in the synthesis of Human Uric Acid Transporter 1 inhibitors which may be used to treat kidney diseases.
  • Therapeutic Function Antihemorrhagic
Technology Process of Benzarone

There total 14 articles about Benzarone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
(2-ethylbenzofuran-3-yl)(4-methoxyphenyl)methanone; In toluene; at 5 - 10 ℃; for 0.5h;
With aluminum (III) chloride; In toluene; at 10 - 60 ℃; for 0.333333h;
Guidance literature:
benzbromarone; With dichloro[1,1′-bis[bis(1,1-dimethylethyl)phosphino]ferrocene-P,P′]palladium; triethylamine; In water; at 20 ℃; for 0.0333333h;
With 1,1,3,3-Tetramethyldisiloxane; for 11.9667h;
DOI:10.1021/ol5037369
Guidance literature:
With lewis acid; In chloroform; at 10 - 30 ℃; for 4h; Solvent; Temperature;
Refernces Edit
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