p-Chlorophenoxyacetyl chloride

Base Information

• Chemical Name: p-Chlorophenoxyacetyl chloride
• CAS No.: 4122-68-3
• Molecular Formula: C8H6Cl2O2
• Molecular Weight: 205.04
• Hs Code.: 29189900
• European Community (EC) Number: 223-923-2
• NSC Number: 20549
• UNII: PZT4V53U3L
• DSSTox Substance ID: DTXSID60194151
• Nikkaji Number: J150.883K
• Wikidata: Q72456384
• Mol file: 4122-68-3.mol

Synonyms:4-Chlorophenoxyacetyl chloride;4122-68-3;p-Chlorophenoxyacetyl chloride;2-(4-chlorophenoxy)acetyl chloride;(4-Chlorophenoxy)acetyl chloride;4-chlorophenoxyacetylchloride;Acetyl chloride, (4-chlorophenoxy)-;PZT4V53U3L;EINECS 223-923-2;MFCD00000727;NSC-20549;UNII-PZT4V53U3L;SCHEMBL105460;(4chlorophenoxy)acetyl chloride;(p-Chlorophenoxy)acetyl chloride;VRBVHQUSAOKVDH-UHFFFAOYSA-;DTXSID60194151;(4-chlorophenoxy)acetyl chlo-ride;4-chlorophenoxyacetic acid chloride;(4-chloro-phenoxy)-acetyl chloride;(4-Chlorophenoxy)acetyl chloride #;NSC20549;STR07060;4-Chlorophenoxyacetyl chloride, 98%;AM9901;NSC 20549;AKOS000346281;Acetyl chloride, 2-(4-chlorophenoxy)-;FT-0618242;(4-Chlorophenoxy)acetyl chloride, tech. 85%;EN300-24757;D89302;A852739

Chemical Property of p-Chlorophenoxyacetyl chloride

Chemical Property:

• Appearance/Colour: clear colorless to yellow liquid
• Vapor Pressure: 0.00965mmHg at 25°C
• Melting Point: 18.8 °C(lit.)
• Refractive Index: n20/D 1.5486(lit.)
• Boiling Point: 264.5 °C at 760 mmHg
• Flash Point: 112.9 °C
• PSA: 26.30000
• Density: 1.363 g/cm³
• LogP: 2.48420
• Storage Temp.: Inert atmosphere,Room Temperature
• Sensitive.: Moisture Sensitive
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 203.9744848
• Heavy Atom Count: 12
• Complexity: 153

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Chlorophenoxyacetyl chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34
• Safety Statements: 23-26-36/37/39-45

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=CC=C1OCC(=O)Cl)Cl
• Uses: 4-Chlorophenoxyacetyl chloride was used in the preparation of:substituted acetophenone derivatives2-(4-chlorophenoxyacetylamino)-3-ethoxycarbonyl[2,3-b]quinuclidine2-(4-chlorophenoxy)-N′-[2-(4-chlorophenoxy)acetyl]acetohydrazide monohydrate

Technology Process of p-Chlorophenoxyacetyl chloride

There total 11 articles about p-Chlorophenoxyacetyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-Chlorophenoxyacetic acid (122-88-3) → 4-chlorophenyloxyacetyl chloride (4122-68-3)

Guidance literature:

With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane;

Reference yield: 91.0%

→ 4-chlorophenyloxyacetyl chloride (4122-68-3)

Guidance literature:

Reference yield: 80.0%

tert-butyl 2-(4-chlorophenoxy)acetate (36304-28-6) → 4-chlorophenyloxyacetyl chloride (4122-68-3)

Guidance literature:

With hydrogenchloride; thionyl chloride; In 1,4-dioxane;

upstream raw materials:

4-Chlorophenoxyacetic acid

4-chloro-phenol

sodium 4-chlorophenolate

tert-butyl 2-(4-chlorophenoxy)acetate

Downstream raw materials:

4-[2-(4-chloro-phenoxy)-acetylamino]-benzoic acid

2-(4-chlorophenoxy)-N-(2-hydroxyethyl)acetamide

N-[(4-chloro-phenoxy)-acetyl]-N-phenyl-glycine

1-(4-chloro-phenoxy)-3-diazo-propan-2-one

Refernces

• 1、 -. "A meclofenoxate hydrochloride preparation method". Paragraph 0035-0040; 0041; 0044. . Retrieved 2019/03/25.
• 2、 Syguda, Anna,Gielnik, Anna,Borkowski, Andrzej,Wo?niak-Karczewska, Marta,Parus, Anna,Piechalak, Aneta,Olejnik, Anna,Marecik, Roman,?awniczak, ?ukasz,Chrzanowski, ?ukasz. "Esterquat herbicidal ionic liquids (HILs) with two different herbicides: Evaluation of activity and phytotoxicity". supporting information. p. 9819 - 9827. Retrieved 2018/06/18.