Technology Process of *)>-2-hydroxy-5-<1-hydroxy-2-<(1-methyl-3-phenylpropyl)amino>ethyl>benzamide hydrochloride
There total 13 articles about *)>-2-hydroxy-5-<1-hydroxy-2-<(1-methyl-3-phenylpropyl)amino>ethyl>benzamide hydrochloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; hydrogen;
palladium dihydroxide;
In
ethanol;
for 2h;
under 2280 Torr;
Ambient temperature;
DOI:10.1021/jm00353a017
- Guidance literature:
-
Multi-step reaction with 4 steps
2: K2CO3 / dimethylformamide / 4 h / Ambient temperature
3: NaBH4 / ethanol / 16 h / Ambient temperature
4: 70 percent / H2, 1 N aq. HCl / 20percent Pd(OH)2/C / ethanol / 2 h / 2280 Torr / Ambient temperature
With
hydrogenchloride; sodium tetrahydroborate; hydrogen; potassium carbonate;
palladium dihydroxide;
In
ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00353a017
- Guidance literature:
-
Multi-step reaction with 6 steps
1: p-TsOH*H2O / benzene / 14 h / Heating
2: NaBH4 / methanol / 16 h / Ambient temperature
4: K2CO3 / dimethylformamide / 4 h / Ambient temperature
5: NaBH4 / ethanol / 16 h / Ambient temperature
6: 70 percent / H2, 1 N aq. HCl / 20percent Pd(OH)2/C / ethanol / 2 h / 2280 Torr / Ambient temperature
With
hydrogenchloride; sodium tetrahydroborate; hydrogen; potassium carbonate; toluene-4-sulfonic acid;
palladium dihydroxide;
In
methanol; ethanol; N,N-dimethyl-formamide; benzene;
DOI:10.1021/jm00353a017