1-Phenazinamine

Base Information

• Chemical Name: 1-Phenazinamine
• CAS No.: 2876-22-4
• Molecular Formula: C12H9N3
• Molecular Weight: 195.224
• Hs Code.: 2933990090
• European Community (EC) Number: 220-719-5
• UNII: Q98GLL9GUC
• DSSTox Substance ID: DTXSID50182941,DTXSID901315538
• Nikkaji Number: J80.584J
• Wikidata: Q83053666
• Mol file: 2876-22-4.mol

Synonyms:1-Phenazinamine;phenazin-1-amine;2876-22-4;1-Aminophenazine;Phenazin-1-ylamine;Phenazine, 1-amino-;CCRIS 3021;1-Phenazinamine (9CI);Phenazin-1(5H)-imine;EINECS 220-719-5;755710-53-3;aminophenazine;1-amino phenazine;Q98GLL9GUC;1,5-dihydrophenazin-1-imine;SCHEMBL252368;SCHEMBL2293195;QWUFXJHVFNRNCU-UHFFFAOYSA-;DTXSID50182941;DTXSID901315538;CAA87622;MFCD00705275;AKOS003625448;BS-16878;LS-102987;CS-0081108;N13381

Chemical Property of 1-Phenazinamine

Chemical Property:

• Vapor Pressure: 1.08E-07mmHg at 25°C
• Melting Point: 201-290 °C
• Refractive Index: 1.6990 (estimate)
• Boiling Point: 432.7°Cat760mmHg
• PKA: 3.40±0.30(Predicted)
• Flash Point: 245.4°C
• PSA: 51.80000
• Density: 1.333g/cm³
• LogP: 2.94640
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 195.079647300
• Heavy Atom Count: 15
• Complexity: 231

Purity/Quality:

99%, ^*data from raw suppliers

Phenazin-1-amine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)N=C3C=CC=C(C3=N2)N

Technology Process of 1-Phenazinamine

There total 22 articles about 1-Phenazinamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

phenazine-1-carboxamide (550-89-0) → phenazin-1-ylamine (2876-22-4)

Guidance literature:

phenazine-1-carboxamide; With bromine; sodium methylate; In tetrahydrofuran; methanol; at -78 - 55 ℃; for 75h;

With sodium hydroxide; In methanol; water; at 90 ℃; for 4h;

Reference yield: 61.0%

tubermycin B (2538-68-3,102646-59-3) → phenazin-1-ylamine (2876-22-4)

Guidance literature:

tubermycin B; With diphenyl phosphoryl azide; triethylamine; In tetrahydrofuran; at 20 ℃; for 3h; Inert atmosphere;

With water; In tetrahydrofuran; for 2h; Inert atmosphere; Reflux;

DOI:10.1039/c3ob42416b

Reference yield: 32.0%

3,4-dihydrophenazin-1(2H)-one oxime → phenazin-1-ylamine (2876-22-4)

Guidance literature:

With potassium hydroxide; acetylene; In dimethyl sulfoxide; at 93 - 96 ℃; for 2h;

DOI:10.1134/S1070428017010316

upstream raw materials:

1-chlorophenazine

phenazine-1-carboxamide

1-nitrophenazine

1-nitro-phenazine 5-oxide

Downstream raw materials:

phenazin-1-ol

Refernces

• 1、 Petrova,Sobenina,Budaev,Ivanov,Samsonov,Tikhonov, A. Ya.,Trofimov. "Formation of 1-aminophenazine from 3,4-dihydrophenazin-1(2H)-one oxime in the system acetylene–KOH–DMSO". . . Retrieved 2017.
• 2、 -. "Phenazine derivative serving as TrxR1 inhibitor, intermediate product, preparation methods of phenazine derivative and intermediate product and application of phenazine derivative". . . Retrieved 2019/09/14.