4,4'-DIETHYLBIPHENYL

Base Information

• Chemical Name: 4,4'-DIETHYLBIPHENYL
• CAS No.: 13049-40-6
• Molecular Formula: C16H18
• Molecular Weight: 210.319
• Hs Code.: 2902909090
• Mol file: 13049-40-6.mol

Synonyms:Biphenyl,4,4'-diethyl- (6CI,7CI,8CI);4,4'-Diethylbiphenyl;p,p'-Diethylbiphenyl;

Chemical Property of 4,4'-DIETHYLBIPHENYL

Chemical Property:

• Melting Point: 82 °C
• Boiling Point: 316.9 °C at 760 mmHg
• Flash Point: 151.2 °C
• PSA: 0.00000
• Density: 0.954 g/cm³
• LogP: 4.47840

Purity/Quality:

98%,99%, ^*data from raw suppliers

4,4''-Diethylbiphenyl ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,4'-DIETHYLBIPHENYL

There total 21 articles about 4,4'-DIETHYLBIPHENYL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4,4'-Dimethoxybiphenyl (2132-80-1) + triethylaluminum (97-93-8) → 4,4'-diethylbiphenyl (13049-40-6)

Guidance literature:

4,4'-Dimethoxybiphenyl; With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; 1,2-bis-(dicyclohexylphosphino)ethane; In di-isopropyl ether; toluene; at 20 ℃; for 0.0833333h; Glovebox; Inert atmosphere;

triethylaluminum; In di-isopropyl ether; toluene; at 120 ℃; for 72h; Glovebox; Inert atmosphere;

DOI:10.1002/anie.201510497

Reference yield: 97.0%

1-bromo-4-ethylbenzene (1585-07-5) → 4,4'-diethylbiphenyl (13049-40-6)

Guidance literature:

With caesium carbonate; In water; at 80 ℃; for 24h; Green chemistry;

DOI:10.1002/cctc.201300893

Reference yield: 93.0%

4-ethylphenylboronic acid (63139-21-9) → 4,4'-diethylbiphenyl (13049-40-6)

Guidance literature:

With [Pd(N-phenylbenzaldimine)(OAc)(PPh₃)]; In tetrahydrofuran; at 20 ℃; for 24h; Schlenk technique;

DOI:10.1039/c4ra09678a

upstream raw materials:

4-ethyl-1-iodobenzene

1-(4'-ethyl-[1,1'-biphenyl]-4-yl)ethan-1-one

ethylbenzene

3,4’-diethyl-1,1’-biphenyl

Downstream raw materials:

1-(4'-ethyl-[1,1'-biphenyl]-4-yl)ethan-1-one

4,4'-diacetylbiphenyl

Refernces

• 1、 Long, Bing-Fan,Qin, Gui-Fang,Huang, Qin,Xiong, Ting,Mi, Yan,Hu, Fei-Long,Yin, Xian-Hong. "Homocoupling of arylboronic acids catalyzed by dinuclear copper(I) complexes under mild conditions". . p. 2639 - 2646. Retrieved 2019.
• 2、 Guo, Mengping,Qi, Liang,Lv, Meiyun,Zhou, Xiuling,Liang, Hui,Chen, Sanbao. "Homocoupling of arylboronic acids catalyzed by a simple hydrophilic palladium(II) complex in aqueous media". . p. 205 - 209. Retrieved 2015.
• 3、 Ishizu,K. et al.. "-". . p. 140 - 143. Retrieved 1973.
• 4、 Margulieux, Grant W.,Semproni, Scott P.,Chirik, Paul J.. "Photochemically induced reductive elimination as a route to a zirconocene complex with a strongly activated N2 ligand". . p. 9189 - 9192,4. Retrieved 2014.
• 5、 Taylor et al.. "". . p. 3215,3216. Retrieved 1973.
• 6、 Ishizu et al.. "". . p. 2808,2809,2810,2812. Retrieved 1969.
• 7、 Nirmala, Muthukumaran,Adinarayana, Mannem,Ramesh, Karupnaswamy,Maruthupandi, Mannarsamy,Vaddamanu, Moulali,Raju, Gembali,Prabusankar, Ganesan. "Water-soluble superbulky (η6- p -cymene) ruthenium(ii) amine: An active catalyst in the oxidative homocoupling of arylboronic acids and the hydration of organonitriles". supporting information. p. 15221 - 15230. Retrieved 2018/09/29.