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Technology Process of 2-[Bis-(2-hydroxy-ethyl)-amino]-2-hydroxymethyl-propane-1,3-diol

2-[Bis-(2-hydroxy-ethyl)-amino]-2-hydroxymethyl-propane-1,3-diol

Base Information Edit
  • Chemical Name:2-[Bis-(2-hydroxy-ethyl)-amino]-2-hydroxymethyl-propane-1,3-diol
  • CAS No.:6976-37-0
  • Molecular Formula:C8H19NO5
  • Molecular Weight:209.24
  • Hs Code.:29221980
  • European Community (EC) Number:230-237-7,686-880-2
  • NSC Number:119932,24868
  • UNII:Q1XC3631CP
  • DSSTox Substance ID:DTXSID6064537
  • Nikkaji Number:J135.733F
  • Wikipedia:Bis-tris_methane
  • Wikidata:Q865956
  • Mol file:6976-37-0.mol
2-[Bis-(2-hydroxy-ethyl)-amino]-2-hydroxymethyl-propane-1,3-diol

Synonyms:2-(bis(2-hydroxyethyl)amino)-2(hydroxymethyl)-1,3-propanediol;bis(2-hydroxyethyl)imino-tris(hydroxymethyl)methane;Bis-Tris;Bistris

Suppliers and Price of 2-[Bis-(2-hydroxy-ethyl)-amino]-2-hydroxymethyl-propane-1,3-diol
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • BIS-TRIS
  • 100g
  • $ 403.00
  • Tocris
  • BIS-TRIS ≥99%
  • 100G
  • $ 139.00
  • TCI Chemical
  • Bis(2-hydroxyethyl)aminotris(hydroxymethyl)methane [Good's buffer component for biological research] >99.0%(HPLC)(T)
  • 250g
  • $ 554.00
  • TCI Chemical
  • Bis(2-hydroxyethyl)aminotris(hydroxymethyl)methane [Good's buffer component for biological research] >99.0%(HPLC)(T)
  • 25g
  • $ 87.00
  • Sigma-Aldrich
  • BIS-TRIS BioPerformance Certified, cell culture tested, suitable for insect cell culture, ≥98.0%
  • 25g
  • $ 52.50
  • Sigma-Aldrich
  • BIS-TRIS ≥98.0% (titration)
  • 25g
  • $ 41.10
  • Sigma-Aldrich
  • BIS-TRIS anhydrous, free-flowing, Redi-Dri , ≥98.0%
  • 100g
  • $ 132.00
  • Sigma-Aldrich
  • BIS-Tris, ULTROL Grade - CAS 6976-37-0 - Calbiochem
  • 100gm
  • $ 128.00
  • Sigma-Aldrich
  • OmniPur BIS TRIS - CAS 6976-37-0 - Calbiochem
  • 100gm
  • $ 128.00
  • Sigma-Aldrich
  • BIS-Tris, ULTROL Grade - CAS 6976-37-0 - Calbiochem Azwitterionicbufferthatexhibitsonlyaverysmallshiftindissociationcons
  • 100 g
  • $ 127.65
Total 146 raw suppliers
Chemical Property of 2-[Bis-(2-hydroxy-ethyl)-amino]-2-hydroxymethyl-propane-1,3-diol Edit
Chemical Property:
  • Appearance/Colour:white/clear crystalline powder 
  • Vapor Pressure:1.19E-10mmHg at 25°C 
  • Melting Point:104 °C(lit.) 
  • Boiling Point:466.2 °C at 760 mmHg 
  • PKA:6.5(at 25℃) 
  • Flash Point:288 °C 
  • PSA：104.39000 
  • Density:1.346 g/cm3 
  • LogP:-3.01130 
  • Storage Temp.:Store at RT. 
  • Sensitive.:Air Sensitive 
  • Solubility.:H2O: 1 M at 20 °C, clear, colorless 
  • Water Solubility.:soluble 
  • XLogP3:-3.3
  • Hydrogen Bond Donor Count:5
  • Hydrogen Bond Acceptor Count:6
  • Rotatable Bond Count:8
  • Exact Mass:209.12632271
  • Heavy Atom Count:14
  • Complexity:125
Purity/Quality:

99% *data from raw suppliers

BIS-TRIS *data from reagent suppliers

Safty Information:
  • Pictogram(s): IrritantXi,HarmfulXn 
  • Hazard Codes:Xi,Xn 
  • Statements: 36/37/38-21/22-20/21/22 
  • Safety Statements: 26-36-36/37/39-22 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Chemical Classes:Nitrogen Compounds -> Amino Alcohols, Other
  • Canonical SMILES:C(CO)N(CCO)C(CO)(CO)CO
  • Uses It is used as a biological buffer, organic synthesize, chemical & pharmaceutical intermediate. It is suitable for fractionation of hemoglobin. Bis Tris is a commonly used biological buffer for very broad usage in biological systems such as diagnostics, electrophoresis and protein based bioprocessing. The pKa of Bis Tris is 6.36 which makes it a good candidate for biological-based formulations.Bis Tris is used in a wide variety of biological applications including protein separation buffers, cell culture media, electrophoresis separations and diagnostic reagent formulations.

Total 8 Pictures about this product

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