m-DL-Sarcolysin

Base Information

• Chemical Name: m-DL-Sarcolysin
• CAS No.: 1088-79-5
• Molecular Formula: C₁₃H₁₈Cl₂N₂O₂
• Molecular Weight: 305.204
• NSC Number: 67782,67781,27381
• UNII: 8BA40E8GDC
• DSSTox Substance ID: DTXSID70862531
• ChEMBL ID: CHEMBL461166
• Mol file: 1088-79-5.mol

Synonyms:m-DL-Sarcolysin;m-DL-Sarcolysine;1088-79-5;rac-meta-Melphalan;MP 267;NSC 27381;Metamelfalan, (+/-)-;8BA40E8GDC;3-(Bis(2-chloroethyl)amino)-DL-phenylalanine;ALANINE, 3-(m-(BIS(2-CHLOROETHYL)AMINO)PHENYL)-, DL-;DL-Phenylalanine, 3-(bis(2-chloroethyl)amino)-;3-(m-(Bis(2-chloroethyl)amino)phenyl)-DL-alanine;NSC-27381;DL-Alanine, 3-(m-(bis(2-chloroethyl)amino)phenyl)-;Metamelfalan [INN:BAN];Metamelfalanum [INN-Latin];DL-Phenylalanine, 3-[bis(2-chloroethyl)amino]-;NSC 67781;3-[bis(2-chloroethyl)amino]phenylalanine;Metamelfalan [BAN:INN];3-(BIS(2-CHLOROETHYL)AMINO)PHENYLALANINE;L-3-(m-(Bis(2-chloroethyl)amino)phenyl)alanine;DL-Alanine, 3-(m-[bis(2-chloroethyl)amino]phenyl)-;Alanine, 3-[m-[bis(2-chloroethyl)amino]phenyl]-, DL-;(S)-3-(3-(Bis-(2-chlorethyl)amino)phenyl)-2-aminopropionsaeure;UNII-8BA40E8GDC;NCIOpen2_008496;NCIOpen2_008580;CHEMBL461166;SCHEMBL2015272;DTXSID70862531;2-amino-3-[3-[bis(2-chloroethyl)amino]phenyl]propanoic acid;WLN: QVYZ1R CN2G2G -DL;NSC27381;NSC67781;NSC67782;LS-15870;LS-15871;PD159714;m-(di-(2-chloro-ethyl)amino]-dl-phenylalanine;PHENYLALANINE, 3-(BIS(2-CHLOROETHYL)AMINO)-

Chemical Property of m-DL-Sarcolysin

Chemical Property:

• Vapor Pressure: 5.2E-10mmHg at 25°C
• Boiling Point: 479.7°Cat760mmHg
• Flash Point: 243.9°C
• Density: 1.32g/cm³
• XLogP3: -0.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 8
• Exact Mass: 304.0745332
• Heavy Atom Count: 19
• Complexity: 273

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC(=C1)N(CCCl)CCCl)CC(C(=O)O)N

Technology Process of m-DL-Sarcolysin

There total 3 articles about m-DL-Sarcolysin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetylamino-{3-[bis-(2-chloro-ethyl)-amino]-benzyl}-malonic acid diethyl ester (103755-30-2) → 3-[bis-(2-chloro-ethyl)-amino]-phenylalanine (1088-79-5)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/ja01521a047

Reference yield:

→ 3-[bis-(2-chloro-ethyl)-amino]-phenylalanine (1088-79-5)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/ja01521a048

Reference yield:

→ 3-[bis-(2-chloro-ethyl)-amino]-phenylalanine (1088-79-5)

Guidance literature:

β-Acetamido-β-(m-nitrophenyl)propionsaeureethylester, 1)H2, Pd-C (-> m-Aminophenylderivat) 2)Ethylenoxid 3)SOCl2, HCl;

upstream raw materials:

acetylamino-{3-[bis-(2-chloro-ethyl)-amino]-benzyl}-malonic acid diethyl ester