2,6-Dichlorbenzylchlorformiat

Base Information

• Chemical Name: 2,6-Dichlorbenzylchlorformiat
• CAS No.: 39545-39-6
• Molecular Formula: C₈H₅Cl₃O₂
• Molecular Weight: 239.485
• Mol file: 39545-39-6.mol

Synonyms:2,6-Dichlorbenzylchlorformiat

Chemical Property of 2,6-Dichlorbenzylchlorformiat

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,6-Dichlorbenzylchlorformiat

There total 1 articles about 2,6-Dichlorbenzylchlorformiat which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phosgene (75-44-5) + 2,6-dichlorobenzyl alcohol (15258-73-8) → 2,6-Dichlorbenzylchlorformiat (39545-39-6)

Guidance literature:

In benzene;

DOI:10.1021/jo00960a027

Reference yield: 69.0%

2,6-Dichlorbenzylchlorformiat (39545-39-6) + 6-(tert-butyl)-8-chloro-2,3-dimethylquinolin-4-ol → 6-(tert-butyl)-8-chloro-2,3-dimethylquinolin-4-yl (2,6-dichlorobenzyl) carbonate

Guidance literature:

With potassium carbonate; In acetone; at 20 ℃;

DOI:10.2174/1570180815666180313121735

Reference yield:

2,6-Dichlorbenzylchlorformiat (39545-39-6) → Nα-Boc-Lys(Nε-2,4-Cl2Z) (83038-58-8)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) aq. NaOH, CuSO₄*5H₂O, (ii) /BRN= 1876321/

2: aq. NaOH / dioxane

With sodium hydroxide; In 1,4-dioxane;

DOI:10.1021/jo00960a027

upstream raw materials:

phosgene

2,6-dichlorobenzyl alcohol

Downstream raw materials:

N^ε-(2,6-Dichlorbenzyloxycarbonyl)-L-lysin

N^α-Boc-Lys(N^ε-2,4-Cl2Z)