1-(3-(pyridin-2-yl)phenyl)ethan-1-one

Base Information

• Chemical Name: 1-(3-(pyridin-2-yl)phenyl)ethan-1-one
• CAS No.: 227178-09-8
• Molecular Formula: C₁₃H₁₁NO
• Molecular Weight: 197.236
• Hs Code.: 2933399990
• Mol file: 227178-09-8.mol

Synonyms:1-(3-(pyridin-2-yl)phenyl)ethan-1-one

Chemical Property of 1-(3-(pyridin-2-yl)phenyl)ethan-1-one

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

1-(3-Pyridin-2-yl-phenyl)-ethanone 95%+ ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(3-(pyridin-2-yl)phenyl)ethan-1-one

There total 8 articles about 1-(3-(pyridin-2-yl)phenyl)ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-bromo-pyridine (109-04-6) + 3-acetylphenylboronic acid → 1-(3-(pyridin-2-yl)phenyl)ethan-1-one (227178-09-8)

Guidance literature:

With palladium diacetate; potassium carbonate; triphenylphosphine; In 1,2-dimethoxyethane; water; for 15h; Reflux; Inert atmosphere; Schlenk technique;

DOI:10.1002/chem.201904927

Reference yield: 92.0%

2-tri-n-butylstannylpyridine (17997-47-6) + 1-(3-Bromophenyl)ethanone (2142-63-4) → 1-(3-(pyridin-2-yl)phenyl)ethan-1-one (227178-09-8)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; In toluene; for 24h; Reflux;

DOI:10.1002/chem.201203687

Reference yield: 90.0%

pyridin-2-yl trifluoromethanesulfonate (65007-00-3) + 3-acetylphenylboronic acid → 1-(3-(pyridin-2-yl)phenyl)ethan-1-one (227178-09-8)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In toluene; for 24h; Reflux; Inert atmosphere;

DOI:10.1039/c2cc37862k

upstream raw materials:

2-bromo-pyridine

2-tri-n-butylstannylpyridine

1-(3-Bromophenyl)ethanone

3'-iodoacetophenone

Downstream raw materials:

1-{2-oxo-2-[30-(200-pyridinyl)phenyl]ethyl}pyridinium iodide

C₂₀H₁₅NO₂

1-phenyl-1-(3-(pyridin-2-yl)phenyl)ethanol

N-[4-acetyl-2-(pyridin-2-yl)phenyl]-4-methylbenzenesulfonamide

Refernces

• 1、 Cheng, Hanchao,Lam, Tsz-Lung,Liu, Yungen,Tang, Zhou,Che, Chi-Ming. "Photoinduced Hydroarylation and Cyclization of Alkenes with Luminescent Platinum(II) Complexes". supporting information. p. 1383 - 1389. Retrieved 2020/11/30.
• 2、 -. "4-SUBSTITUTED-2-THIAZOLE AMIDES AS ANTIVIRAL AGENTS". . . Retrieved 2021/01/22.