Sebacamide

Base Information

• Chemical Name: Sebacamide
• CAS No.: 1740-54-1
• Molecular Formula: C10H20 N2 O2
• Molecular Weight: 200.281
• Hs Code.: 2924199090
• European Community (EC) Number: 217-103-3
• NSC Number: 1178
• UNII: 26EXS6JUE8
• DSSTox Substance ID: DTXSID60169743
• Nikkaji Number: J126.215G
• Wikidata: Q83039485
• Mol file: 1740-54-1.mol

Synonyms:Decanediamide;Sebacamide;1740-54-1;decandiamid;26EXS6JUE8;AI3-16818;NSC 1178;NSC-1178;EINECS 217-103-3;Sebacic acid diamide;decanedioic acid amide;SEBACAMIDE, TECH.;UNII-26EXS6JUE8;SCHEMBL51304;DTXSID60169743;NSC1178;Sebacamide, technical grade, 85%;AKOS024319679;AS-80526;FT-0652234;E77569;A811602

Chemical Property of Sebacamide

Chemical Property:

• Vapor Pressure: 4.43E-09mmHg at 25°C
• Boiling Point: 472°Cat760mmHg
• Flash Point: 239.3°C
• PSA: 86.18000
• Density: 1.026g/cm³
• LogP: 2.47840
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 9
• Exact Mass: 200.152477885
• Heavy Atom Count: 14
• Complexity: 161

Purity/Quality:

98%,99%, ^*data from raw suppliers

SEBACAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCCCC(=O)N)CCCC(=O)N

Technology Process of Sebacamide

There total 13 articles about Sebacamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

1,10-decanedioic acid (111-20-6,26776-29-4) → sebacamide (1740-54-1)

Guidance literature:

With ammonium chloride; triethylamine; 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; In methanol; at 20 ℃; for 6h;

DOI:10.1246/cl.2008.1190

Reference yield: 67.9%

sebacoyl chloride (111-19-3) → sebacamide (1740-54-1)

Guidance literature:

With ammonium acetate; In acetone; at 30 - 42 ℃; for 1h;

Reference yield:

sebaconitrile (1871-96-1) → sebacamide (1740-54-1)

Guidance literature:

With dihydrogen peroxide; potassium carbonate; In dimethyl sulfoxide;

DOI:10.1016/j.jct.2006.04.004

upstream raw materials:

1,10-decanedioic acid

ammonium thiocyanate

6-amino-6-oxohexanoic acid

sodium methylate

Downstream raw materials:

sebaconitrile

1,10-decanedioic acid

1,10-Decanediol

diaminodecane

Refernces

• 1、 -. "Method for producing aliphatic diamine (by machine translation)". Paragraph 0053. . Retrieved 2019/07/05.
• 2、 -. "Corresponding amine nitrile and method of manufacturing thereof". Paragraph 0125; 0126; 0127; 0128. . Retrieved 2018/07/15.