Pharmakon1600-01503237

Base Information Edit

Chemical Name:Pharmakon1600-01503237
CAS No.:3093-35-4
Molecular Formula:C24H32ClFO5
Molecular Weight:454.966
Hs Code.:2937220000
NSC Number:758413
ChEMBL ID:CHEMBL3039407
Mol file:3093-35-4.mol

Synonyms:SR-05000001841;Spectrum_001579;Spectrum2_001540;Spectrum3_001577;Spectrum4_000180;Spectrum5_001257;BSPBio_003114;KBioGR_000699;KBioSS_002059;DivK1c_000637;SPECTRUM1503237;SPBio_001360;CHEMBL3039407;SCHEMBL10019829;HMS501P19;KBio1_000637;KBio2_002059;KBio2_004627;KBio2_007195;KBio3_002614;NINDS_000637;HMS1922K21;Pharmakon1600-01503237;CCG-39318;NSC758413;IDI1_000637;NCGC00178287-01;AB00052456_02;SR-05000001841-1;SR-05000001841-3;BRD-A88138582-001-03-0

Suppliers and Price of Pharmakon1600-01503237

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Halcinonide
200mg
$ 235.00

TCI Chemical
Halcinonide
25MG
$ 42.00

TCI Chemical
Halcinonide
100MG
$ 124.00

Sigma-Aldrich
Halcinonide United States Pharmacopeia (USP) Reference Standard
200mg
$ 366.00

Medical Isotopes, Inc.
Halcinonide
5 mg
$ 950.00

DC Chemicals
Halcinonide >98%
100 mg
$ 350.00

Crysdot
Halcinonide 98+%
250mg
$ 223.00

ChemScene
Halcinonide 99.87%
200mg
$ 290.00

ChemScene
Halcinonide 99.87%
50mg
$ 90.00

ChemScene
Halcinonide 99.87%
10mg
$ 50.00

Total 150 raw suppliers

Chemical Property of Pharmakon1600-01503237 Edit

Chemical Property:

Vapor Pressure:4.38E-15mmHg at 25°C
Melting Point:264-265° (dec)
Refractive Index:1.566
Boiling Point:564.3 °C at 760 mmHg
PKA:13.19±0.70(Predicted)
Flash Point:295.1 °C
PSA：72.83000
Density:1.31 g/cm³
LogP:3.88930
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly)
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:454.1922300
Heavy Atom Count:31
Complexity:887

Purity/Quality:

99% ^*data from raw suppliers

Halcinonide ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 63
Safety Statements: 36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(OC2CC3C4CCC5=CC(=O)CCC5(C4(C(CC3(C2(O1)C(=O)CCl)C)O)F)C)C
Isomeric SMILES:CC1(O[C@@H]2CC3C4CCC5=CC(=O)CCC5(C4(C(CC3([C@@]2(O1)C(=O)CCl)C)O)F)C)C
Indications The drug is suitable for treatment of contact dermatitis, atopic dermatitis, lichen,the small size of psoriasis, lichen, heat rash, genital atrophic lichen sclerosus, non-parasitic prurigo, ring granuloma, discoid lupus erythematosus, non-facial seborrheic dermatitis, mycosis fungoides pruritus symptomatic .It is also used for the treatment of insect bites, parasitic prurigo through specific treatment. It has a good effect on the treatment of psoriasis . Halcinonide (Halog, Halog-E) is a synthetic fluorinated corticosteroid.
Uses Cortical hormone drugs for the treatment of psoriasis and eczema dermatitis . 2H-Naphth[2'',1'':4,5]indeno[1,2-d][1,3]dioxole Pregn-4-ene-3,20-dione Deriv. is a by-product from the synthesis of 4-Fluorotriamcinolone Acetonide (F598640) an analog of Fluocinolone Acetonide (F455800); a glucocorticoid and anti-inflammatory agent. Anti-inflammatory (topical).
Therapeutic Function Topical corticosteroid

Technology Process of Pharmakon1600-01503237

There total 9 articles about Pharmakon1600-01503237 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.5%