(4-Azaniumylphenyl)-hydroxyarsinate

Base Information

• Chemical Name: (4-Azaniumylphenyl)-hydroxyarsinate
• CAS No.: 98-50-0
• Molecular Formula: C6H8AsNO3
• Molecular Weight: 217.056
• Hs Code.: Oral rat LD50: >1000 mg/kg
• Metabolomics Workbench ID: 147551
• Mol file: 98-50-0.mol

Synonyms:(4-azaniumylphenyl)-hydroxyarsinate

Chemical Property of (4-Azaniumylphenyl)-hydroxyarsinate

Chemical Property:

• Appearance/Colour: off-white fine crystalline powder
• Vapor Pressure: 5.34E-12mmHg at 25°C
• Melting Point: ≥300 °C(lit.)
• Boiling Point: 528.5 °C at 760 mmHg
• PKA: pK1: ca 2;pK2: 4.02;pK3: 8.62 (25°C)
• Flash Point: 273.4 °C
• PSA: 83.55000
• Density: 1.9571
• LogP: -0.58900
• Solubility.: Sparingly soluble in water, soluble in concentrated mineral acids, alkali carbonate solutions, alcohol and diethyl ether. Practically insoluble in acetone, benzene and chloroform.
• Water Solubility.: SLIGHTLY SOLUBLE IN COLD WATER
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 216.972013
• Heavy Atom Count: 11
• Complexity: 168

Purity/Quality:

98%, ^*data from raw suppliers

4-ArsanilicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T,N
• Hazard Codes: T,N
• Statements: 23/25-50/53
• Safety Statements: 20/21-28-45-60-61-28A

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC(=CC=C1[NH3+])[As](=O)(O)[O-]
• Uses: 4-Aminophenylarsonic acid is an organoarsenic compound. 4-Aminophenylarsonic acid is a highly toxic contaminant and can be found in plants growing in contaminated soil. 4-Aminophenylarsonic acid was used as an additive in animal feed. It has also been used in treating dysentery in swine as well as having potential chemotherapeutic activity. Arsanilic acid reacts essentially analogously to phenylarsonic acid. According to Chandelle, in the presence of relatively large amounts of accompanying ions the determination of zirconium gives more accurate results with this reagent than with phenylarsonic acid. This statement has not yet been confirmed. Nevertheless, the reagent is much more widely used than any other arsonic acid derivative. manufacture of medicinal arsenicals.
• Therapeutic Function: Antibacterial

Technology Process of (4-Azaniumylphenyl)-hydroxyarsinate

There total 23 articles about (4-Azaniumylphenyl)-hydroxyarsinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

orthoarsenic acid (7778-39-4,121471-47-4,1327-52-2) + aniline (62-53-3) → p-aminophenylarsonic acid (98-50-0) + bis-(4-amino-phenyl)-arsinic acid (6309-25-7)

Guidance literature:

at 170 - 200 ℃;

Reference yield:

nitarsone (98-72-6) → p-aminophenylarsonic acid (98-50-0)

Guidance literature:

With sodium hydroxide; hydrogen; palladium; under 1520 - 2280 Torr;

Reference yield:

orthoarsenic acid (7778-39-4,121471-47-4,1327-52-2) + aniline (62-53-3) → p-aminophenylarsonic acid (98-50-0)

Guidance literature:

at 170 - 200 ℃;

upstream raw materials:

nitarsone

anilinium arsenate

aniline

orthoarsenic acid

Downstream raw materials:

(4-[2]furyl-phenyl)-arsonic acid

[4-(3-chloro-1,4-dioxo-1,4-dihydro-[2]naphthylamino)-phenyl]-arsonic acid

(4,4'-ureylene-diphenyl)-bis-arsonic acid

(4-benzothiazol-2-ylamino-phenyl)-arsonic acid

Refernces

• 1、 -. "Process for formulating a synthetic drug for use in animal feed, and resulting formulation". . . Retrieved 2008/06/13.