2-Propoxyethylamine

Base Information

• Chemical Name: 2-Propoxyethylamine
• CAS No.: 42185-03-5
• Molecular Formula: C5H13NO
• Molecular Weight: 103.164
• Hs Code.: 2922199090
• European Community (EC) Number: 255-699-7
• DSSTox Substance ID: DTXSID20195003
• Nikkaji Number: J278.352E
• Wikidata: Q72502535
• Mol file: 42185-03-5.mol

Synonyms:2-Propoxyethylamine;42185-03-5;2-Propoxyethanamine;2-n-propoxyethylamine;2-AMINOETHYLPROPYLETHER;2-n-PROPOXY ETHYLAMINE;2-propoxyethan-1-amine;2-Aminoethyl Propyl Ether;O-Propylethanolamine;2-AMINOETHYL N-PROPYL ETHER;EINECS 255-699-7;MFCD00047955;Ethanamine, 2-propoxy-;2-propoxy-ethylamine;2-Propoxyethanamine #;2-Propoxy-1-ethanamine;[2-(propyloxy)ethyl]amine;SCHEMBL162682;2-Propoxyethanamine, AldrichCPR;DTXSID20195003;STR08697;AKOS005256740;BP-10794;FT-0639769;D88415;EN300-386123

Chemical Property of 2-Propoxyethylamine

Chemical Property:

• Vapor Pressure: 8.12mmHg at 25°C
• Refractive Index: 1.4126
• Boiling Point: 134.3 °C at 760 mmHg
• PKA: 8.89±0.10(Predicted)
• Flash Point: 30.7 °C
• PSA: 35.25000
• Density: 0.851 g/cm³
• LogP: 1.07200
• XLogP3: 0
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 103.099714038
• Heavy Atom Count: 7
• Complexity: 31.3

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-N-Propoxyethylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 11-34-41-22
• Safety Statements: 16-26-36/37/39-39

MSDS Files:

Useful:

• Canonical SMILES: CCCOCCN

Technology Process of 2-Propoxyethylamine

There total 4 articles about 2-Propoxyethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sodium n-propoxide (6819-41-6) + 2-bromoethylamine hydrobromide (2576-47-8) → 2-propoxyethanamine (42185-03-5)

Guidance literature:

With propan-1-ol; ethanol;

DOI:10.1021/jo01100a015

Reference yield:

propan-1-ol (71-23-8) → 2-propoxyethanamine (42185-03-5)

Guidance literature:

Reference yield:

ethyleneimine (151-56-4,9002-98-6) + propan-1-ol (71-23-8) → 2-propoxyethanamine (42185-03-5)

Guidance literature:

Multistep reaction; (i) BF₃-Et₂O, (ii) /BRN= 1098242/, (iii) KOH;

upstream raw materials:

sodium n-propoxide

2-bromoethylamine hydrobromide

ethyleneimine

propan-1-ol

Downstream raw materials:

C₂₄H₃₀N₆O₅

C₂₄H₃₀N₆O₅

Refernces

• 1、 -. "HIV INTEGRASE INHIBITORS". . . Retrieved 2015/09/22.