Etazolate

Base Information

• Chemical Name: Etazolate
• CAS No.: 51022-77-6
• Molecular Formula: C14H19N5O2
• Molecular Weight: 289.337
• UNII: I89Y79062L
• DSSTox Substance ID: DTXSID4048434
• Nikkaji Number: J10.285G
• Wikipedia: Etazolate
• Wikidata: Q5402458
• NCI Thesaurus Code: C73334
• Pharos Ligand ID: V2SRBT3CT4ZT
• ChEMBL ID: CHEMBL356388
• Mol file: 51022-77-6.mol

Synonyms:Etazolate;Etazolate Hydrochloride;Hydrochloride, Etazolate;SQ 20009;SQ-20009;SQ20009

Chemical Property of Etazolate

Chemical Property:

• Appearance/Colour: Off-White Solid
• Vapor Pressure: 1.61E-07mmHg at 25°C
• Melting Point: 193-194 ºC
• Refractive Index: 1.605
• Boiling Point: 427.6 ºC at 760 mmHg
• PKA: 9.94±0.70(Predicted)
• Flash Point: 212.4 ºC
• PSA: 81.40000
• Density: 1.25 g/cm³
• LogP: 2.50860
• Storage Temp.: Store at RT
• Solubility.: H2O: >20 mg/mL Solutions should be freshly prepared.
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 6
• Exact Mass: 289.15387487
• Heavy Atom Count: 21
• Complexity: 397

Purity/Quality:

98%Min ^*data from raw suppliers

Etazolate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN1C2=NC=C(C(=C2C=N1)NN=C(C)C)C(=O)OCC
• Uses: An inhibitor of phosphodiesterase IV, about 8 times more active for cAMP than cGMP PDE inhibitor An inhibitor of phosphodiesterase IV, about 8 times more active for cAMP than cGMP.

Technology Process of Etazolate

There total 1 articles about Etazolate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 1-ethyl-4-(isopropylidene-hydrazino)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester (51022-77-6)

Guidance literature:

Reference yield:

1-ethyl-4-(isopropylidene-hydrazino)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester (51022-77-6)

Guidance literature:

Hydrolyse - Geschwindigk.-Konst., Produktvert.;

DOI:10.1002/jps.2600670633

Refernces

• 1、 -. "Molecular target of neurotoxicity". . . Retrieved 2008/06/13.