DL-Ornithine hydrochloride

Base Information

• Chemical Name: DL-Ornithine hydrochloride
• CAS No.: 1069-31-4
• Molecular Formula: C5H12N2O2^.HCl
• Molecular Weight: 168.623
• Hs Code.: 29224985
• European Community (EC) Number: 213-956-0,245-259-2
• NSC Number: 118361,118360,25163
• DSSTox Substance ID: DTXSID90920541
• Metabolomics Workbench ID: 71559
• ChEMBL ID: CHEMBL1972294
• Mol file: 1069-31-4.mol

Synonyms:1069-31-4;DL-Ornithine hydrochloride;2,5-Diaminopentanoic acid hydrochloride;DL-ORNITHINE HCL;DL-Ornithine monohydrochloride;H-DL-Orn-OH.HCl;Ornithine, monohydrochloride;DL-Ornithine, hydrochloride;MFCD00065398;2,5-diaminopentanoic acid;hydrochloride;Ornithine DL-form HCl;DL-Ornithine, monohydrochloride;Ornithine, monohydrochloride, DL-;Ornithine DL-form monohydrochloride;EINECS 213-956-0;NSC 25163;(2R)-2,5-diaminopentanoic acid;AI3-26557;L-ORNITHINE HCL (3,3,4,4,5,5-D6);(+/-)-2,5-Diaminopentanoic acid monohydrochloride;ORNITHINE HCL;H-D-Orn-OH HCl;NSC118360;C5H12N2O2.ClH;1346617-00-2;(2S)-2,5-diaminopentanoic acid hydrochloride;C5-H12-N2-O2.Cl-H;MFCD00012917;NSC-118360;DL-Ornithinexhydrochloride;DL-Ornithine xhydrochloride;DL-Ornithine (hydrochloride);SCHEMBL534810;SGCUT00223;WLN: Z3YZVQ &GH -L;CHEMBL1972294;Ornithine, hydrochloride (1:1);DTXSID90920541;BCP13629;D(+)-2,5-Diamino-pentanoic acid;L(+)-2,5-Diamino-pentanoic acid;NSC25163;to_000074;ORNITHINE HYDROCHLORIDE,(DL);AC1496;NSC-25163;NSC118361;Ornithine--hydrogen chloride (1/1);AKOS008056531;DL-Ornithine monohydrochloride, ~99%;CCG-213889;NSC-118361;(4-Amino-1-carboxybutyl)azanium;chloride;2,5-Diaminovaleric Acid Monohydrochloride;AS-12881;SY005810;SY007936;2,5-bis(azanyl)pentanoic acid hydrochloride;2,5-Diaminopentanoic Acid Monohydrochloride;AM20080016;CS-0136494;FT-0625497;FT-0625590;FT-0627979;FT-0673307;FT-0695773;O0063;EN300-20082;DL-Ornithine monohydrochloride, >=99.0% (AT);A801537;A821021;J-001677;Z104476736

Chemical Property of DL-Ornithine hydrochloride

Chemical Property:

• Appearance/Colour: white crystalline powder
• Vapor Pressure: 0.00015mmHg at 25°C
• Melting Point: 291 °C
• Boiling Point: 308.7 °C at 760 mmHg
• Flash Point: 140.5 °C
• PSA: 89.34000
• Density: 1.165 g/cm3
• LogP: 1.33980
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility.: Aqueous Acid (Slightly), Water (Slightly)
• Water Solubility.: soluble
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 168.0665554
• Heavy Atom Count: 10
• Complexity: 95

Purity/Quality:

99% ^*data from raw suppliers

DL-OrnithineHydrochloride ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Biological Agents -> Amino Acids and Derivatives
• Canonical SMILES: C(CC(C(=O)O)N)CN.Cl
• Uses: Erythro-3-hydroxy-DL-ornithine monohydrochloride is used as a reagent to synthesize DL-Capreomycidine, a guanidine (HCl)-containing amino acid that is a component of antituberculous peptides. DL-Ornithine monohydrochloride may be used as a starting material in the synthesis of (-)-(1-2H)putrescine dihydrochloride via enzymatic decarboxylation.

Technology Process of DL-Ornithine hydrochloride

There total 7 articles about DL-Ornithine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2,5-diamino-pentanoic acid 9-bora-bicyclo[3.3.1]non-9-yl ester; hydrochloride → DL-ornithine hydrochloride (1069-31-4,36630-89-4)

Guidance literature:

With ethylenediamine; In tetrahydrofuran; for 0.0166667h; Heating;

DOI:10.1021/ol017241b

Reference yield: 88.0%

ethyl-(2RS)-2-acetamido-2-cyano-5-phthalimidopentanoate (20850-34-4) → DL-ornithine hydrochloride (1069-31-4,36630-89-4)

Guidance literature:

With hydrogenchloride; for 15h; Heating;

DOI:10.1021/ja00225a033

Reference yield: 85.0%

(R)-methyl 2-acetamido-7-chloroheptanoate → (R)-2,5-diaminopentanoic acid dihydrochloride (1069-31-4,3184-13-2,6211-16-1,15160-12-0,16682-12-5,20724-48-5,22834-83-9,26982-21-8,66837-02-3,99815-05-1,36630-89-4)

Guidance literature:

With hydrogenchloride; In water; for 10h; Reflux;

DOI:10.1039/c5ob01111f

upstream raw materials:

ethyl-(2RS)-2-acetamido-2-cyano-5-phthalimidopentanoate

phthalimido-(3-phthalimido-propyl)-malonic acid diethyl ester

2,5-Bis(methoxycarbonylamino)valeriansaeure-methylester

methyl 2,5-dibromovalerate

Downstream raw materials:

Arg

ornithine p.chlorohippurate

(3S)-Aminopiperidin-2-one

(R)-(+)-3-Amino-2-piperidinon

Refernces

• 1、 Dent 3rd., William H,Erickson, W Randal,Fields, Stephen C,Parker, Marshall H,Tromiczak, Eric G. "9-BBN: An amino acid protecting group for functionalization of amino acid side chains in organic solvents.". . p. 1249 - 1251. Retrieved 2007/10/03.
• 2、 Martinkus,Tann,Gould. "The biosynthesis of the streptolidine moiety in streptothricin F". . p. 3493 - 3505. Retrieved 2007/10/02.