(R)-(-)-2-(2-fluorophenyl)-2-methyloxirane

Base Information Edit

Chemical Name:(R)-(-)-2-(2-fluorophenyl)-2-methyloxirane
CAS No.:1251069-75-6
Molecular Formula:C₉H₉FO
Molecular Weight:152.168
Hs Code.:
Mol file:1251069-75-6.mol

Synonyms:(R)-(-)-2-(2-fluorophenyl)-2-methyloxirane

Suppliers and Price of (R)-(-)-2-(2-fluorophenyl)-2-methyloxirane

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-(-)-2-(2-fluorophenyl)-2-methyloxirane Edit

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-(-)-2-(2-fluorophenyl)-2-methyloxirane

There total 2 articles about (R)-(-)-2-(2-fluorophenyl)-2-methyloxirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 74249-17-5
(2R)-2-(2-fluorophenyl)oxirane

: 74-88-4
methyl iodide

: 1251069-75-6
(R)-(-)-2-(2-fluorophenyl)-2-methyloxirane

Guidance literature:: (2R)-2-(2-fluorophenyl)oxirane; With sec.-butyllithium; In tetrahydrofuran; cyclohexane; at -98.16 ℃; for 0.25h; Inert atmosphere;

methyl iodide; In tetrahydrofuran; cyclohexane; at -98.16 - 19.84 ℃; Inert atmosphere;
DOI:10.1002/chem.201000897

Reference yield:

: 344-73-0
1-fluoro-2-(prop-1-en-2-yl)benzene

: 1251069-75-6
(R)-(-)-2-(2-fluorophenyl)-2-methyloxirane

: C₉H₉FO

Guidance literature:: With C₂₆H₃₆F₆FeN₆O₆S₂; C₃₀H₄₄N₄O₈; dihydrogen peroxide; In water; acetonitrile; at -30 ℃; for 0.5h; Overall yield = 79 %; Optical yield = 86 %ee; enantioselective reaction;
DOI:10.1039/c7sc00099e