(R)-methyl(1-naphthyl)phenylsilane

Base Information

• Chemical Name: (R)-methyl(1-naphthyl)phenylsilane
• CAS No.: 1025-08-7
• Molecular Formula: C₁₇H₁₆Si
• Molecular Weight: 248.4
• Mol file: 1025-08-7.mol

Synonyms:(R)-methyl(1-naphthyl)phenylsilane

Chemical Property of (R)-methyl(1-naphthyl)phenylsilane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-methyl(1-naphthyl)phenylsilane

There total 28 articles about (R)-methyl(1-naphthyl)phenylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(S)-(-)-[(-)-menthyloxy](1-naphthyl)methylphenylsilane (35742-37-1) → (R)-methyl(1-naphthyl)phenylsilane (1025-08-7)

Guidance literature:

With lithium aluminium tetrahydride; In dibutyl ether; at 80 - 90 ℃; for 24h; optical yield given as %ee;

DOI:10.1002/adsc.200900230

Reference yield: 80.0%

(S)-(-)-[(-)-menthyloxy](1-naphthyl)methylphenylsilane (35742-37-1) → (+)-methyl-(α-naphthyl)-phenylsilane (1025-08-7,1025-09-8,7427-12-5,17037-10-4)

Guidance literature:

With lithium aluminium tetrahydride; In dibutyl ether; at 80 - 90 ℃; for 18h;

Reference yield: 75.0%

α-naphthylphenylmethyl-(-)-menthoxysilane → (R)-methyl(1-naphthyl)phenylsilane (1025-08-7)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; dibutyl ether; at 80 ℃; for 12h; Inert atmosphere;

DOI:10.1002/anie.201508669

upstream raw materials:

dimethoxy(methyl)phenylsilane

1-naphthylmagnesiumbromide

1-naphthylphenylsilane

methylmagnesium bromide

Downstream raw materials:

(S)-(4,4-Dimethyl-penta-1,2-dienyl)-methyl-naphthalen-1-yl-phenyl-silane

α-naphtylphenylmethylsilyl t-butylphenylthiophosphinate

α-naphtylphenylmethylsilyl t-butylphenyl-phosphinate

(E)-3-((R)-Methyl-naphthalen-1-yl-phenyl-silanyl)-prop-2-en-1-ol

Refernces

• 1、 Wang, Kaikai,Zhou, Jimei,Jiang, Yuting,Zhang, Miaomiao,Wang, Chao,Xue, Dong,Tang, Weijun,Sun, Huamin,Xiao, Jianliang,Li, Chaoqun. "Selective Manganese-Catalyzed Oxidation of Hydrosilanes to Silanols under Neutral Reaction Conditions". . p. 6380 - 6384. Retrieved 2019/05/06.
• 2、 Kim, Youngchan,Chang, Sukbok. "Borane-Catalyzed Reductive α-Silylation of Conjugated Esters and Amides Leaving Carbonyl Groups Intact". . p. 218 - 222. Retrieved 2016/01/25.