p-toluenesulphonic-phenylacetic anhydride

Base Information

• Chemical Name: p-toluenesulphonic-phenylacetic anhydride
• CAS No.: 26926-32-9
• Molecular Formula: C₁₅H₁₄O₄S
• Molecular Weight: 290.34
• Mol file: 26926-32-9.mol

Synonyms:p-toluenesulphonic-phenylacetic anhydride

Chemical Property of p-toluenesulphonic-phenylacetic anhydride

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of p-toluenesulphonic-phenylacetic anhydride

There total 1 articles about p-toluenesulphonic-phenylacetic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

tetrabutylammonium 2-phenylacetate (22359-89-3) + p-toluenesulfonyl chloride (98-59-9) → p-toluenesulphonic-phenylacetic anhydride (26926-32-9)

Guidance literature:

In dichloromethane; for 4h;

Reference yield: 70.0%

ethanol (64-17-5) + p-toluenesulphonic-phenylacetic anhydride (26926-32-9) → Ethyl 2-phenylethanoate (101-97-3)

Guidance literature:

In dichloromethane; for 18h; Ambient temperature;

Reference yield: 65.0%

p-toluenesulphonic-phenylacetic anhydride (26926-32-9) + glycine ethyl ester hydrochloride (5680-79-5,883886-67-7) → methyl 2-(2-phenylacetamido)acetate (5259-87-0)

Guidance literature:

In dichloromethane; for 18h; Ambient temperature;

upstream raw materials:

tetrabutylammonium 2-phenylacetate

p-toluenesulfonyl chloride

Downstream raw materials:

Ethyl 2-phenylethanoate

methyl 2-(2-phenylacetamido)acetate

N-isopropyl-2-phenylacetamide

isopropyl phenylacetate

Refernces