Uroporphyrin II

Base Information

• Chemical Name: Uroporphyrin II
• CAS No.: 531-42-0
• Molecular Formula: C₄₀H₃₈N₄O₁₆
• Molecular Weight: 830.759
• UNII: 284LO13GDK
• Nikkaji Number: J11.354I
• Mol file: 531-42-0.mol

Synonyms:Uroporphyrin II;Uroporphyrin 2 isomer;284LO13GDK;UNII-284LO13GDK;531-42-0;2,8,12,18-Porphinetetrapropionic acid, 3,7,13,17-tetrakis(carboxymethyl)-;21H,23H-Porphine-2,8,12,18-tetrapropanoic acid, 3,7,13,17-tetrakis(carboxymethyl)-;SCHEMBL4319887

Chemical Property of Uroporphyrin II

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 1155.5°Cat760mmHg
• Flash Point: 652.6°C
• PSA: 354.70000
• Density: 1.291g/cm³
• LogP: 0.64060
• XLogP3: -1
• Hydrogen Bond Donor Count: 10
• Hydrogen Bond Acceptor Count: 18
• Rotatable Bond Count: 20
• Exact Mass: 830.22828114
• Heavy Atom Count: 60
• Complexity: 1510

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C2C(=C(C(=CC3=NC(=CC4=NC(=CC5=C(C(=C1N5)CC(=O)O)CCC(=O)O)C(=C4CC(=O)O)CCC(=O)O)C(=C3CCC(=O)O)CC(=O)O)N2)CCC(=O)O)CC(=O)O

Technology Process of Uroporphyrin II

There total 2 articles about Uroporphyrin II which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + ethyl 3-(4-ethoxycarbonylmethyl-1H-pyrrol-3-yl)-propionate (367967-01-9) → uroporphyrin (18273-06-8) + 3,3',3'',3'''-(3,7,13,17-tetrakis-carboxymethyl-21H,23H-porphine-2,8,12,18-tetrayl)-tetrakis-propionic acid (531-42-0) + uroporphyrin I (607-14-7) + 3-[(5Z,10Z,14Z,19Z)-7,13,18-Tris-(2-carboxy-ethyl)-3,8,12,17-tetrakis-carboxymethyl-porphyrin-2-yl]-propionic acid

Guidance literature:

formaldehyd; ethyl 3-(4-ethoxycarbonylmethyl-1H-pyrrol-3-yl)-propionate; With toluene-4-sulfonic acid; In benzene; for 4h; Heating;

With oxygen; In benzene; at 20 ℃; for 2h;

With sodium hydroxide; In ethanol; at 20 ℃; Title compound not separated from byproducts;

DOI:10.1016/S0040-4039(01)01160-1

Reference yield:

→ 3,3',3'',3'''-(3,7,13,17-tetrakis-carboxymethyl-21H,23H-porphine-2,8,12,18-tetrayl)-tetrakis-propionic acid (531-42-0)

Guidance literature:

Inkubation von Suspensionen P. Shermani / 8-Aminolaevulinsaeure;

upstream raw materials:

formaldehyd

ethyl 3-(4-ethoxycarbonylmethyl-1H-pyrrol-3-yl)-propionate

Refernces

• 1、 Müller,Dieterle,Siebke. "Production of porphyrins by Propionibacterium shermanii". . p. 307 - 309. Retrieved 2007/10/05.