N-methylideneisopropylamine

Base Information

• Chemical Name: N-methylideneisopropylamine
• CAS No.: 77037-04-8
• Molecular Formula: C₄H₉N
• Molecular Weight: 71.1222
• Mol file: 77037-04-8.mol

Synonyms:N-methylideneisopropylamine

Chemical Property of N-methylideneisopropylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-methylideneisopropylamine

There total 1 articles about N-methylideneisopropylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

N-methylpropan-2-amine (4747-21-1) → methyl-1 ethylideneamine (6407-34-7,19885-74-6) + N-methylideneisopropylamine (77037-04-8)

Guidance literature:

With N-chloro-succinimide; Adipic acid; potassium tert-butylate; under 0.004 Torr; Title compound not separated from byproducts; 1.) 2 h, RT 2.) 2 h, 60 deg C;

DOI:10.1016/S0040-4020(01)86145-7

Reference yield: 86.0%

N-methylideneisopropylamine (77037-04-8) + C18H17NO3 → (E)-methyl 2-(3-isopropyl-1-(4-methoxyphenyl)-5-phenylimidazolidin-4-ylidene)acetate (1601484-05-2)

Guidance literature:

With copper(l) chloride; In dichloromethane; at 20 ℃; for 12h;

DOI:10.1016/j.tet.2014.03.063

Reference yield: 82.0%

N-methylideneisopropylamine (77037-04-8) + (S)-(-)-N-(1-phenylethyl)-2-hydroxyimino-3-oxobutyramide (1312613-66-3) → (S)-N-(1-phenylethyl)-1-isopropyl-5-methyl-3-oxido-1H-imidazole-4-carboxamide (1312613-68-5)

Guidance literature:

In ethanol; for 5h; Reflux;

DOI:10.1016/j.tetasy.2011.04.005

upstream raw materials:

N-methylpropan-2-amine

Downstream raw materials:

N-<(Nitrobenzoyloxy)methyl>-N-nitrosoisopropylamin

1,3,5-Triisopropyl-1,3,5-triazacyclohexane

C₁₇H₂₆N₂O₄

ethyl (E)-4-((2-(tert-butylamino)-2-oxoethyl)-(isopropyl)amino)-2-(4-((2-(tert-butylamino)-2-oxoethyl)(isopropyl)amino)-3-methoxy-5-nitrobenzylidene)-4-oxobutanoate

Refernces