4-(2-methylmaleamido)hippuric acid

Base Information

• Chemical Name: 4-(2-methylmaleamido)hippuric acid
• CAS No.: 83560-91-2
• Molecular Formula: C₁₄H₁₄N₂O₆
• Molecular Weight: 306.275
• Mol file: 83560-91-2.mol

Synonyms:4-(2-methylmaleamido)hippuric acid

Chemical Property of 4-(2-methylmaleamido)hippuric acid

Chemical Property:

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Technology Process of 4-(2-methylmaleamido)hippuric acid

There total 1 articles about 4-(2-methylmaleamido)hippuric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-Aminohippuric acid (61-78-9) + citraconic acid anhydride (616-02-4) → 4-(2-methylmaleamido)hippuric acid (83560-91-2)

Guidance literature:

With acetic acid; for 3h; Heating;

DOI:10.1021/jm00355a017

Reference yield: 54.0%

4-(2-methylmaleamido)hippuric acid (83560-91-2) → 4-(2-methylmaleimido)hippuric acid (83560-85-4)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; toluene; Heating;

DOI:10.1021/jm00355a017

upstream raw materials:

p-Aminohippuric acid

citraconic acid anhydride

Downstream raw materials:

4-(2-methylmaleimido)hippuric acid

Refernces