CYCLOHEXYLIDENECYCLOHEXANE

Base Information

• Chemical Name: CYCLOHEXYLIDENECYCLOHEXANE
• CAS No.: 4233-18-5
• Molecular Formula: C12H20
• Molecular Weight: 164.291
• Hs Code.: 2902199090
• Mol file: 4233-18-5.mol

Synonyms:dicyclohexylidene;Bicyclohexyliden;bicyclohexylidene;1,1'-bicyclohexylidene;A6921;

Chemical Property of CYCLOHEXYLIDENECYCLOHEXANE

Chemical Property:

• Melting Point: 55 °C
• Boiling Point: 236-237 °C
• Flash Point: 81.2oC
• PSA: 0.00000
• Density: 0.0109 g/cm3(Temp: 15 °C)
• LogP: 4.21120

Purity/Quality:

98%,99%, ^*data from raw suppliers

Dicyclohexylidene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Total 1 MSDS from other Authors

Useful:

• Uses: Dicyclohexylidene is a versatile reactant made from Cyclohexanone (C987980), which is a useful intermediate used in the synthesis of Lomustine (L469440), an effective antitumor agent.

Technology Process of CYCLOHEXYLIDENECYCLOHEXANE

There total 14 articles about CYCLOHEXYLIDENECYCLOHEXANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

benzophenone (119-61-9) + cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) → bicyclohexylidene (4233-18-5) + 1,1-diphenylmethylenecyclohexane (30125-24-7) + 1,1,2,2-tetraphenylethylene (632-51-9)

Guidance literature:

With pyridine; titanium tetrachloride; zinc; In tetrahydrofuran; Heating;

DOI:10.1021/jo061644d

Reference yield: 70.0%

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + 4-Hydroxyacetophenone (99-93-4) → 4-(1-cyclohexylideneethyl)phenol + C16H16O2 + bicyclohexylidene (4233-18-5)

Guidance literature:

With pyridine; titanium tetrachloride; zinc; In tetrahydrofuran; Heating;

DOI:10.1021/jo061644d

Reference yield: 69.0%

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + 1-(4-methoxyphenyl)ethanone (100-06-1) → 1-(1-cyclohexylideneethyl)-4-methoxybenzene + bicyclohexylidene (4233-18-5) + 4,4'-(but-2-ene-2,3-diyl)bis(methoxybenzene) (895-37-4)

Guidance literature:

With pyridine; titanium tetrachloride; zinc; In tetrahydrofuran; Heating;

DOI:10.1021/jo061644d

upstream raw materials:

Tetrahydro-4H-pyran-4-one

cyclohexanone

sulfuric acid

cyclohexanol

Downstream raw materials:

Cyclohexanone diperoxide

cyclohexanone

1-methoxy-1-hydroperoxycyclohexane

C₂₂H₂₇NO₃

Refernces

• 1、 Khenkin, Alexander M.,Neumann, Ronny. "Nitrosonium salts, NO+X- (X = B(3,5-diCF 3Ph)4- or PW12O40 3-), as electrophilic catalysts for alkene activation in arene alkylation and dimerization reactions". supporting information; body text. p. 11876 - 11877. Retrieved 2009/02/05.
• 2、 Mundy, Bradford P.,Srinivasa, Ramanujan,Kim, Youseung,Dolph, Thomas,Warnet, Ronald J.. "Studies on the Pinacol Coupling Reaction". . p. 1657 - 1661. Retrieved 2007/10/02.