Benzo[b]benzo[4,5]thieno[2,3-d]thiophene

Base Information

• Chemical Name: Benzo[b]benzo[4,5]thieno[2,3-d]thiophene
• CAS No.: 248-70-4
• Molecular Formula: C14H8 S2
• Molecular Weight: 240.35
• Hs Code.: 2934999090
• Mol file: 248-70-4.mol

Synonyms:Benzo[b]thieno[3,2-b]benzo[b]thiophene;Benzothieno[3,2-b]benzothiophene; Thianaphtheno[3,2-b]thianaphthene;[1]Benzothiopheno[3,2-b][1]benzothiophene

Chemical Property of Benzo[b]benzo[4,5]thieno[2,3-d]thiophene

Chemical Property:

• Vapor Pressure: 2.83E-07mmHg at 25°C
• Melting Point: 218.0 to 222.0 °C
• Boiling Point: 432.3°C at 760 mmHg
• Flash Point: 162.1°C
• PSA: 56.48000
• Density: 1.407g/cm³
• LogP: 5.26920
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

98%+ ^*data from raw suppliers

Benzo[b]benzo[4,5]thieno[2,3-d]thiophene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzo[b]benzo[4,5]thieno[2,3-d]thiophene

There total 10 articles about Benzo[b]benzo[4,5]thieno[2,3-d]thiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

(E)-2,2'-dichlorostilbene (25144-38-1) → benzthieno[3,2-b]benzothiophene (248-70-4) + 2-phenylbenzo[b]thiophene (1207-95-0) + 2-chloro-2'-mercaptostilbene (1254175-17-1) + 2-(2-chlorophenyl)-2,3-dihydrobenzo[b]thiophene (1254175-16-0)

Guidance literature:

With sulfur; In 1-methyl-pyrrolidin-2-one; at 180 ℃; for 4h; Inert atmosphere;

DOI:10.1016/j.tetlet.2010.07.152

Reference yield: 30.0%

(E)-2,2'-dibromostilbene (56667-12-0) → benzthieno[3,2-b]benzothiophene (248-70-4) + 2-phenylbenzo[b]thiophene (1207-95-0) + dibenzo[b,f]thiepine (257-13-6)

Guidance literature:

With sodium sulphide nonahydrate; sulfur; In 1-methyl-pyrrolidin-2-one; at 180 ℃; for 16h; Inert atmosphere;

DOI:10.1016/j.tetlet.2010.07.152

Reference yield: 23.0%

(E)-2,2'-dichlorostilbene (25144-38-1) → benzthieno[3,2-b]benzothiophene (248-70-4) + 2-chloro-2'-mercaptostilbene (1254175-17-1)

Guidance literature:

With sulfur; In 1-methyl-pyrrolidin-2-one; at 120 ℃; for 16h;

DOI:10.1016/j.tetlet.2010.07.152

upstream raw materials:

1,2-di(1-hydroxycyclohexyl)acetylene

Benzotrichlorid

benzil

2-chloro-2'-mercaptostilbene

Downstream raw materials:

2-(o-Sulfinophenyl)-3-hydroxybenzothiophene 1,1-Dioxide

Potassium 2-(3-Hydroxy-1,1-dioxido-2-benzothienyl)benzenesulfinate

2-(1,1-Dioxo-3-propylamino-1H-1λ⁶-benzo[b]thiophen-2-yl)-benzenesulfinic acid; compound with propylamine

2-[3-(2-Hydroxy-ethylamino)-1,1-dioxo-1H-1λ⁶-benzo[b]thiophen-2-yl]-benzenesulfinic acid; compound with 2-amino-ethanol

Refernces

• 1、 Saito, Masahiko,Yamamoto, Tatsuya,Osaka, Itaru,Miyazaki, Eigo,Takimiya, Kazuo,Kuwabara, Hirokazu,Ikeda, Masaaki. "Facile synthesis of [1]benzothieno[3,2-b]benzothiophene from o-dihalostilbenes". scheme or table. p. 5277 - 5280. Retrieved 2010/11/03.
• 2、 Choi, Keun Soo,Sawada, Kanji,Dong, Haibiao,Hoshino, Masamatsu,Nakayama, Yuzo. "A ONE-POT SYNTHESIS OF SUBSTITUTED THIENOTHIOPHENES AND SELENOLOSELENOPHENES". . p. 143 - 150. Retrieved 2007/10/02.