trans-Pt(acetate)2(cyclohexylamine)NH₃

Base Information

• Chemical Name: trans-Pt(acetate)2(cyclohexylamine)NH₃
• CAS No.: 921593-87-5
• Molecular Formula: C₁₀H₂₂N₂O₄Pt
• Molecular Weight: 429.376
• Mol file: 921593-87-5.mol

Synonyms:trans-Pt(acetate)2(cyclohexylamine)NH₃

Chemical Property of trans-Pt(acetate)2(cyclohexylamine)NH₃

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-Pt(acetate)2(cyclohexylamine)NH₃

There total 3 articles about trans-Pt(acetate)2(cyclohexylamine)NH₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

cis-Pt(NH3)(cyclohexylamine)I2 (146924-19-8,111716-25-7) + silver(I) acetate (563-63-3) → cis-Pt(acetate)2(cyclohexylamine)NH3 (921593-87-5)

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃; for 14h;

DOI:10.1021/acs.inorgchem.9b02796

Reference yield:

(OC6-6-12)-bis(acetato-O)amminedichloro(cyclohexylamine)platinum(IV) (129580-63-8,146924-14-3,146924-15-4,152375-90-1,177470-23-4,177470-24-5,281654-38-4) → trans-Pt(acetate)2(cyclohexylamine)NH3 (921593-87-5)

Guidance literature:

With ascorbic acid; In water; byproducts: dehydroascorbate; reaction of ascorbic acid with Pt-complex was studied in aq. perchloratemedium pH 4.50-6.28 at 15-35°C in the presence of Na2H2EDTA; detected by NMR and UV/VIS spectroscopy; Kinetics;

DOI:10.1039/a909484i

Reference yield:

trans,cis,cis-PtCl2(acetate)2(cyclohexylamine)NH3 (129580-63-8,146924-14-3,146924-15-4,152375-90-1,177470-23-4,177470-24-5,281654-38-4) → cis-Pt(acetate)2(cyclohexylamine)NH3 (921593-87-5)

Guidance literature:

With ascorbic acid; In water; byproducts: dehydroascorbate; reaction of ascorbic acid with Pt-complex was studied in aq. perchloratemedium pH 4.00-7.0 at 10-30°C in the presence of Na2H2EDTA; detected by NMR and UV/VIS spectroscopy; Kinetics;

DOI:10.1039/a909484i

upstream raw materials:

(OC₆-6-12)-bis(acetato-O)amminedichloro(cyclohexylamine)platinum(IV)

trans,cis,cis-PtCl₂(acetate)2(cyclohexylamine)NH₃

cis-Pt(NH₃)(cyclohexylamine)I₂

silver(I) acetate

Refernces

• 1、 Sinisi, Marilù,Intini, Francesco P.,Natile, Giovanni. "Dependence of the reduction products of platinum(IV) prodrugs upon the configuration of the substrate, bulk of the carrier ligands, and nature of the reducing agent". . p. 9694 - 9704. Retrieved 2012/10/29.