prostaglandin B1

Base Information

• Chemical Name: prostaglandin B1
• CAS No.: 13345-51-2
• Molecular Formula: C₂₀H₃₂O₄
• Molecular Weight: 336.472
• Hs Code.: 2937500000
• UNII: 1TYI1PJ64T
• DSSTox Substance ID: DTXSID001347609
• Nikkaji Number: J16.061J
• Wikidata: Q27103232
• Metabolomics Workbench ID: 2474,201024
• ChEMBL ID: CHEMBL1561148
• Mol file: 13345-51-2.mol

Synonyms:PGB1;prostaglandin B1

Chemical Property of prostaglandin B1

Chemical Property:

• Vapor Pressure: 1.65E-13mmHg at 25°C
• Refractive Index: 1.549
• Boiling Point: 531.4 °C at 760 mmHg
• PKA: 4.77±0.10(Predicted)
• Flash Point: 289.2 °C
• PSA: 74.60000
• Density: 1.101 g/cm³
• LogP: 4.56850
• Storage Temp.: −20°C
• Solubility.: acetone: 20 mg/mL, clear, colorless to very faintly yellow
• XLogP3: 4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 13
• Exact Mass: 336.23005950
• Heavy Atom Count: 24
• Complexity: 462

Purity/Quality:

98%Min ^*data from raw suppliers

Prostaglandin B1 ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCCCCC(C=CC1=C(C(=O)CC1)CCCCCCC(=O)O)O
• Isomeric SMILES: CCCCC[C@@H](/C=C/C1=C(C(=O)CC1)CCCCCCC(=O)O)O
• Uses: Prostaglandin B1 is a novel microbial biopolymer which has been shown to improve the longevity of type 2 diabetic rodents. Oligomers of prostaglandin B1 inhibit arachidonic acid mobilization in human neutrophils and endothelial cells.

Technology Process of prostaglandin B1

There total 1 articles about prostaglandin B1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ PGB1 (13345-51-2)

Guidance literature:

PGE(1), KOH;

Reference yield:

PGB1 (13345-51-2) + p-phenylbenzyl bromide (2567-29-5) → Prostaglandin B(1)-p-phenylbenzylester (55930-81-9)

Guidance literature:

With silver(l) oxide;

Reference yield:

PGB1 (13345-51-2) + bromo-acetic acid biphenyl-4-yl ester (55987-39-8) → 7-[2-((E)-(S)-3-Hydroxy-oct-1-enyl)-5-oxo-cyclopent-1-enyl]-heptanoic acid biphenyl-4-yloxycarbonylmethyl ester (55931-13-0)

Guidance literature:

With silver(l) oxide;

Downstream raw materials:

Prostaglandin B⁽¹⁾-p-phenylbenzylester

7-[2-((E)-(S)-3-Hydroxy-oct-1-enyl)-5-oxo-cyclopent-1-enyl]-heptanoic acid biphenyl-4-yloxycarbonylmethyl ester

Prostaglandin B⁽¹⁾-p-phenylphenacylester

Prostaglandin B⁽¹⁾-p-bromphenacylester

Refernces