ETHYL-D5-AMINE

Base Information

• Chemical Name: ETHYL-D5-AMINE
• CAS No.: 17616-24-9
• Molecular Formula: C2H2D5N
• Molecular Weight: 50.0446
• Mol file: 17616-24-9.mol

Synonyms:Ethyl-d5-amine(8CI);Ethyl-1,1,2,2,2-d5-amine;

Chemical Property of ETHYL-D5-AMINE

Chemical Property:

• Vapor Pressure: 1130mmHg at 25°C
• Refractive Index: 1.372
• Boiling Point: 14.20 °C at 760 mmHg
• PSA: 26.02000
• Density: 0.768 g/cm³
• LogP: 0.66530

Purity/Quality:

99% ^*data from raw suppliers

Ethylamine-d5 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ETHYL-D5-AMINE

There total 2 articles about ETHYL-D5-AMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

[D3]acetonitrile (2206-26-0) → <(1,1,2,2,2-D5)ethyl>amine (17616-24-9)

Guidance literature:

With deutero lithium aluminiumhydride;

DOI:10.1021/ac300439w

Reference yield:

-ethyl phthalimide (121195-20-8) → <(1,1,2,2,2-D5)ethyl>amine (17616-24-9)

Guidance literature:

With potassium hydroxide; at 300 ℃; Yield given;

Reference yield: 90.0%

<(1,1,2,2,2-D5)ethyl>amine (17616-24-9) + C15H19BrFNO4 → C17H21(2)H5BrFN2O3

Guidance literature:

<(1,1,2,2,2-D5)ethyl>amine; C₁₅H₁₉BrFNO₄; In methanol; at 50 ℃; for 1h;

With methanol; sodium tetrahydroborate; at 20 ℃; for 14h;

upstream raw materials:

-ethyl phthalimide

[D₃]acetonitrile

Refernces

• 1、 Schindler, Birgit K.,Koslitz, Stephan,Meier, Swetlana,Belov, Vladimir N.,Koch, Holger M.,Weiss, Tobias,Bruening, Thomas,Kaefferlein, Heiko U.. "Quantification of four major metabolites of embryotoxic N -methyl- and N -ethyl-2-pyrrolidone in human urine by cooled-injection gas chromatography and isotope dilution mass spectrometry". . p. 3787 - 3794. Retrieved 2012.