Quinolinium, 1-ethyl-2-[(1-ethyl-2(1H)-quinolinylidene)methyl]-, iodide

Base Information

• Chemical Name: Quinolinium, 1-ethyl-2-[(1-ethyl-2(1H)-quinolinylidene)methyl]-, iodide
• CAS No.: 977-96-8
• Molecular Formula: C23H23 N2 . I
• Molecular Weight: 454.354
• Hs Code.: 29334900
• Mol file: 977-96-8.mol

Synonyms:1,1'-diethyl-2,2'-cyanine;1,1'-diethyl-2,2'-cyanine iodide;1-ethyl-2-((1-ethyl-2(1H)-quinolylidene)methyl)quinolinium;bromide of pseudoisocyanine;chloride of pseudoisocyanine;decynium 22;diethylpseudoisocyanine;iodide of pseudoisocyanine;NK 1046;NK-1046;NK1046;pseudocyanine;pseudoisocyanine

Chemical Property of Quinolinium, 1-ethyl-2-[(1-ethyl-2(1H)-quinolinylidene)methyl]-, iodide

Chemical Property:

• Appearance/Colour: dark red crystals
• Melting Point: 273 °C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 8.81000
• Density: g/cm³
• LogP: 1.23570
• Storage Temp.: room temp
• Sensitive.: Light Sensitive
• Solubility.: Soluble to 10 mM in dimethyl sulfoxide.
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 454.09060
• Heavy Atom Count: 26
• Complexity: 464

Purity/Quality:

98%,99%, ^*data from raw suppliers

Decynium 22 ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T,T+
• Statements: 23/24/25-36/37/38-26/28-21
• Safety Statements: 45-36/37-28-26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN1C(=CC2=[N+](C3=CC=CC=C3C=C2)CC)C=CC4=CC=CC=C41.[I-]
• Uses: 1,1'-Diethyl-2,2'-cyanine Iodide is a potent inhibitor of potent extraneuronal monoamine transporter EMT. It inhibits 1-Methyl-4-phenylpyridinium (MPP+), toxic metabolite of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine that induces apoptosis in cerebellar granule neurons (CGNs). 1,1'-Diethyl-2,2'-cyanine iodide is used to inhibit 1-methyl-4-phenylpyridinium (MPP+), toxic metabolite of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine that induces apoptosis in cerebellar granule neurons (CGNs). 1,1′-Diethyl-2,2′-cyanine iodide has been used as an absorber in a method to correct the fluorescence excitation-emission matrix (EEM).

Technology Process of Quinolinium, 1-ethyl-2-[(1-ethyl-2(1H)-quinolinylidene)methyl]-, iodide

There total 5 articles about Quinolinium, 1-ethyl-2-[(1-ethyl-2(1H)-quinolinylidene)methyl]-, iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-ethyl-2-(ethylthio)quinolinium iodide (50745-64-7) → decynium 22 (977-96-8)

Guidance literature:

With pyridine;

Reference yield:

1-ethyl-2-methylquinolinium iodide (606-55-3) + 1-ethyl-2-iodoquinolinium iodide (4800-58-2) → decynium 22 (977-96-8)

Guidance literature:

With ethanol; triethylamine;

Reference yield:

1-ethyl-2-phenylsulfanyl-quinolinium; iodide → decynium 22 (977-96-8)

Guidance literature:

With pyridine;

upstream raw materials:

1-ethyl-2-methylquinolinium iodide

1-ethyl-2-iodoquinolinium iodide

1-ethyl-2-(ethylthio)quinolinium iodide