1,2-EPOXYCYCLOHEPTANE

Base Information

• Chemical Name: 1,2-EPOXYCYCLOHEPTANE
• CAS No.: 286-45-3
• Molecular Formula: C7H12 O
• Molecular Weight: 112.172
• Hs Code.: 2932999099
• European Community (EC) Number: 206-009-8
• DSSTox Substance ID: DTXSID60951266
• Nikkaji Number: J99.887G
• Mol file: 286-45-3.mol

Synonyms:1,2-Epoxycycloheptane;Cycloheptane, 1,2-epoxy-; Cycloheptene epoxide; Cycloheptene, oxide;Epoxycycloheptane

Chemical Property of 1,2-EPOXYCYCLOHEPTANE

Chemical Property:

• Vapor Pressure: 5.24mmHg at 25°C
• Refractive Index: n20/D 1.464
• Boiling Point: 148.9°Cat760mmHg
• Flash Point: 30°C
• PSA: 12.53000
• Density: 0.983g/cm³
• LogP: 1.71790
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 112.088815002
• Heavy Atom Count: 8
• Complexity: 80.4

Purity/Quality:

99% ^*data from raw suppliers

8-Oxabicyclo[5.1.0]octane ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: 10-20/21/22-34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1CCC2C(O2)CC1

Technology Process of 1,2-EPOXYCYCLOHEPTANE

There total 29 articles about 1,2-EPOXYCYCLOHEPTANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Cycloheptene (628-92-2,45509-99-7) → 8-oxabicyclo[5.1.0]octane (286-45-3)

Guidance literature:

With [Ni^II(tetrakis(2,6-di(n-butoxy)phenyl)porphyrinato)]; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃; for 0.166667h; Inert atmosphere; Schlenk technique;

DOI:10.1002/chem.201702750

Reference yield: 98.0%

→ 8-oxabicyclo[5.1.0]octane (286-45-3)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 4h; Heating;

DOI:10.1021/jo00320a012

Reference yield: 82.0%

trans-cycloheptane-1,2-diol (13553-19-0) → 8-oxabicyclo[5.1.0]octane (286-45-3)

Guidance literature:

With sodium hydroxide; p-toluenesulfonyl chloride; benzyltriethylammonium bromide; In dichloromethane; at 25 ℃; for 0.166667h;

DOI:10.1055/s-1985-31416

upstream raw materials:

peracetic acid

Cycloheptene

cycloheptane

2-chloro-cycloheptanol

Downstream raw materials:

trans-2-Ethinylcycloheptanol

(1S,2S)-2-Dimethylamino-cycloheptanol

trans-2-(Phenylethinyl)cycloheptanol

cycloheptanol

Refernces

• 1、 Shylesh, Sankaranarayana Pillai,Jia, Mingjun,Seifert, Andreas,Adappa, Sridhar,Ernst,Thiel, Werner R.. "The enhanced catalytic activity and stability of oxodiperoxomolybdenum- modified mesoporous organosilicas in selective epoxidation reactions". . p. 717 - 719. Retrieved 2009.
• 2、 Jurado, Maria Jose,Gracia, Maria Dolores,Campelo, Juan Manuel,Luque, Rafael,Marinas, Jose Maria,Romero, Antonio Angel. "Selective epoxidation of alkenes using highly active V-SBA-15 materials: Microwave vs. conventional heating". . p. 8603 - 8609. Retrieved 2009.
• 3、 Kokotos, Christoforos G.,Kokotou, Maroula G.,Lotter, Dominik,Sparr, Christof,Triandafillidi, Ierasia. "Aldehyde-catalyzed epoxidation of unactivated alkenes with aqueous hydrogen peroxide". . p. 10191 - 10196. Retrieved 2021/08/12.
• 4、 Feng, Xuanyu,Song, Yang,Chen, Justin S.,Xu, Ziwan,Dunn, Soren J.,Lin, Wenbin. "Rational Construction of an Artificial Binuclear Copper Monooxygenase in a Metal-Organic Framework". supporting information. p. 1107 - 1118. Retrieved 2021/01/25.