2-Tert-butylsulfanylethylazanium;chloride

Base Information

• Chemical Name: 2-Tert-butylsulfanylethylazanium;chloride
• CAS No.: 60116-77-0
• Molecular Formula: C6H16ClNS
• Molecular Weight: 169.719
• Hs Code.: 2930909090
• Mol file: 60116-77-0.mol

Synonyms:D89178

Chemical Property of 2-Tert-butylsulfanylethylazanium;chloride

Chemical Property:

• Vapor Pressure: 0.696mmHg at 25°C
• Melting Point: 195-197 °C
• Boiling Point: 185.5 °C at 760 mmHg
• Flash Point: 66 °C
• PSA: 51.32000
• LogP: 2.97910
• Water Solubility.: Soluble in water
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 169.0691984
• Heavy Atom Count: 9
• Complexity: 56

Purity/Quality:

98%min ^*data from raw suppliers

2-(tert-Butylthio)ethylamine Hydrochloride ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)SCC[NH3+].[Cl-]

Technology Process of 2-Tert-butylsulfanylethylazanium;chloride

There total 1 articles about 2-Tert-butylsulfanylethylazanium;chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.58%

2-mercaptoethylamine hydrochloride (156-57-0) + tert-butyl alcohol (75-65-0) → <2-(tert-butylthio)ethyl>amine hydrochloride (60116-77-0)

Guidance literature:

With hydrogenchloride; at 100 ℃; for 16h;

DOI:10.1080/10426500600614824

Reference yield: 78.0%

<2-(tert-butylthio)ethyl>amine hydrochloride (60116-77-0) + N-phenyl-benzimidoyl chloride (4903-36-0) → C6H5-C{NH(CH2)2StBu}=NC6H5 (1361456-17-8)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1039/c2dt11097k

Reference yield: 61.4%

<2-(tert-butylthio)ethyl>amine hydrochloride (60116-77-0) + 2-(2-bromo-phenyl)-4,4-dimethyl-4,5-dihydro-oxazole (32664-13-4) → NC(CH3)2CH2OCC6H4NHC2H4SC(CH3)3

Guidance literature:

With potassium phosphate; copper(l) iodide; triethylamine; L-proline; In dimethyl sulfoxide; at 110 ℃; for 14h; Inert atmosphere;

DOI:10.1039/b907549f

upstream raw materials:

2-mercaptoethylamine hydrochloride

tert-butyl alcohol

Downstream raw materials:

C₆H₅-C{NH(CH₂)2StBu}=NC₆H₅

Refernces

• 1、 Fujita, Mikako,Otsuka, Masami,Sugiura, Yukio. "Metal-chelating inhibitors of a zinc finger protein HIV-EP1. Remarkable potentiation of inhibitory activity by introduction of SH groups". . p. 503 - 507. Retrieved 2007/10/03.