Tryptazan

Base Information

• Chemical Name: Tryptazan
• CAS No.: 526-30-7
• Molecular Formula: C₁₀H₁₁N₃O₂
• Molecular Weight: 205.216
• Hs Code.: 2933990090
• NSC Number: 1460
• UNII: A634R39190
• DSSTox Substance ID: DTXSID90871741
• Nikkaji Number: J6.658C
• Wikidata: Q27273684
• ChEMBL ID: CHEMBL1988860
• Mol file: 526-30-7.mol

Synonyms:Tryptazan;526-30-7;3-Indazolealanine;2-amino-3-(2H-indazol-3-yl)propanoic acid;NSC1460;2-Amino-3-(3-indazolyl)propionic acid;2-Amino-3-(1H-indazol-3-yl)propanoic acid;3-(1H-indazol-3-yl)alanine;26988-90-9;NSC-1460;A634R39190;1H-Indazole-3-propanoic acid, .alpha.-amino-;DL-Tryptazan;NSC 1460;1H-Indazole-3-propanoic acid, alpha-amino-;UNII-A634R39190;DL-TRYPTAZAN;TRYPTAZAN [MI];INDAZOLE-3-ALANINE;2-Amino-3-(1H-indazol-3-yl)-propionic acid;1H-Indazole-3-propanoic acid, alpha-amino-, (+-)-;SCHEMBL1519993;CHEMBL1988860;TRYPTAZAN, (+/-)-;DTXSID90871741;NCI60_000990;2-Amino-3-(1H-indazol-3-yl)propanoicacid;1H-Indazole-3-propionic acid, alpha-amino-;CS-0020629;1H-Indazole-3-propionic acid, .alpha.-amino-;EN300-1829408;Q27273684

Chemical Property of Tryptazan

Chemical Property:

• Vapor Pressure: 7.21E-05mmHg at 25°C
• Boiling Point: 329.3°C at 760 mmHg
• Flash Point: 152.9°C
• PSA: 92.00000
• Density: 1.434g/cm³
• LogP: 1.21760
• XLogP3: -1.7
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 205.085126602
• Heavy Atom Count: 15
• Complexity: 247

Purity/Quality:

98%min ^*data from raw suppliers

TRYPTAZAN 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(NN=C2C=C1)CC(C(=O)O)N

Technology Process of Tryptazan

There total 4 articles about Tryptazan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-acetylamino-3-(1(2)H-indazol-3-yl)-propionic acid (148452-28-2) → 2-amino-3-(1(2)H-indazol-3-yl)-propionic acid (526-30-7,26988-90-9)

Guidance literature:

With barium dihydroxide;

DOI:10.1021/ja01128a042

Reference yield:

(1(2)H-indazol-3-ylmethyl)-trimethyl-ammonium; iodide → 2-amino-3-(1(2)H-indazol-3-yl)-propionic acid (526-30-7,26988-90-9)

Guidance literature:

Multi-step reaction with 4 steps

2: aq. NaOH solution

4: Ba(OH)2

With barium dihydroxide; sodium hydroxide;

DOI:10.1021/ja01128a042

Reference yield:

acetylamino-(1(2)H-indazol-3-ylmethyl)-malonic acid (855650-67-8) → 2-amino-3-(1(2)H-indazol-3-yl)-propionic acid (526-30-7,26988-90-9)

Guidance literature:

Multi-step reaction with 2 steps

2: Ba(OH)2

With barium dihydroxide;

DOI:10.1021/ja01128a042

upstream raw materials:

2-acetylamino-3-(1⁽²⁾H-indazol-3-yl)-propionic acid

acetylamino-(1⁽²⁾H-indazol-3-ylmethyl)-malonic acid

acetylamino-(1⁽²⁾H-indazol-3-ylmethyl)-malonic acid diethyl ester