1,4-di-p-tolylbutane

Base Information

• Chemical Name: 1,4-di-p-tolylbutane
• CAS No.: 7568-23-2
• Molecular Formula: C₁₈H₂₂
• Molecular Weight: 238.373
• Mol file: 7568-23-2.mol

Synonyms:1,4-di-p-tolylbutane

Chemical Property of 1,4-di-p-tolylbutane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,4-di-p-tolylbutane

There total 18 articles about 1,4-di-p-tolylbutane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

ethene (74-85-1) + 4-tolyl iodide (624-31-7) → 1,4-di-p-tolylbutane (7568-23-2)

Guidance literature:

With (1,2-dimethoxyethane)dichloronickel(II); N,N,N,N,-tetramethylethylenediamine; (4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(2-phenylpyridine(-1H))-iridium(III) hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In acetonitrile; at 25 ℃; for 24h; under 760.051 Torr; Reagent/catalyst; Catalytic behavior; Schlenk technique; Sealed tube; Irradiation;

DOI:10.1016/j.chempr.2018.10.006

Reference yield: 89.0%

ethene (74-85-1) + para-bromotoluene (106-38-7) → 1,4-di-p-tolylbutane (7568-23-2)

Guidance literature:

With (1,2-dimethoxyethane)dichloronickel(II); N,N,N,N,-tetramethylethylenediamine; (4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(2-phenylpyridine(-1H))-iridium(III) hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In acetonitrile; at 25 ℃; for 24h; under 760.051 Torr; Schlenk technique; Sealed tube; Irradiation;

DOI:10.1016/j.chempr.2018.10.006

Reference yield: 87.0%

di-p-tolylbutadiyne (22666-07-5) → 1,4-di-p-tolylbutane (7568-23-2)

Guidance literature:

With palladium on activated charcoal; tetrabutylammomium bromide; water; sodium hydroxide; silicon; at 100 ℃; for 24h;

DOI:10.1002/cplu.201800131

upstream raw materials:

1,4-bis[4-(bromomethyl)phenyl]butane

1,4-bis(4-tolyl)butane-1,4-dione

diazomethane

<2,2>-paracyclophane-1,10-dione

Downstream raw materials:

7-methyl-1-(4-methylphenyl)naphthalene

Refernces

• 1、 Li, Jiesheng,Luo, Yixin,Cheo, Han Wen,Lan, Yu,Wu, Jie. "Photoredox-Catalysis-Modulated, Nickel-Catalyzed Divergent Difunctionalization of Ethylene". supporting information. p. 192 - 203. Retrieved 2019/01/21.
• 2、 Le Bailly, Bryden A. F.,Greenhalgh, Mark D.,Thomas, Stephen P.. "Iron-catalysed, hydride-mediated reductive cross-coupling of vinyl halides and Grignard reagents". supporting information; experimental part. p. 1580 - 1582. Retrieved 2012/03/26.