2-methylsulfanylethanamine

Base Information

• Chemical Name: 2-methylsulfanylethanamine
• CAS No.: 6950-53-4
• Molecular Formula: C3H9 N S . Cl H
• Molecular Weight: 127.638
• Hs Code.: 2930909090
• Mol file: 6950-53-4.mol

Synonyms:Ethylamine,2-(methylthio)-, hydrochloride (8CI); 2-(Methylsulfanyl)ethylaminehydrochloride; S-Methyl-2-(aminoethyl)mercaptan monohydrochloride;S-Methylcysteamine hydrochloride

Chemical Property of 2-methylsulfanylethanamine

Chemical Property:

• Melting Point: 120 °C
• PSA: 51.32000
• LogP: 1.81040
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

2-(Methylthio)ethanamineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-methylsulfanylethanamine

There total 2 articles about 2-methylsulfanylethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

tert-butyl (2-(methylthio)ethyl)carbamate (174360-08-8) → 2‐(methylsulfanyl)ethan‐1‐amine hydrochloride (6950-53-4)

Guidance literature:

With hydrogenchloride; In diethyl ether; at 0 ℃; for 4h;

DOI:10.1071/CH13701

Reference yield:

(2-aminoethyl)methylsulfide (18542-42-2) → 2‐(methylsulfanyl)ethan‐1‐amine hydrochloride (6950-53-4)

Guidance literature:

With hydrogenchloride; In methanol; water; for 0.166667h;

DOI:10.1016/j.bbrc.2010.11.052

Reference yield: 91.0%

6-chloro-2-(3-chloro-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl)-8-methyl-4H-benzo[d][1,3]oxazin-4-one (500011-83-6) + 2‐(methylsulfanyl)ethan‐1‐amine hydrochloride (6950-53-4) → N-(2-(2-(methylthio)ethylcarbamoyl)-4-chloro-6-methylphenyl)-3-chloro-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide

Guidance literature:

With triethylamine; In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.1071/CH13701

upstream raw materials:

tert-butyl (2-(methylthio)ethyl)carbamate

(2-aminoethyl)methylsulfide

Downstream raw materials:

C₆H₅-C{NH(CH₂)2SMe}=NC₆H₅

6-(5-((2-(methylthio)ethylamino)methyl)furan-2-yl)-N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-4-quinazolinamine

tert-butyl (2-(methylthio)ethyl)carbamate

C₂₆H₃₈N₄S₂

Refernces

• 1、 -. "INDOLYLMETHYL-MORPHOLINE DERIVATIVES AS KINASE INHIBITORS". Page/Page column 69. . Retrieved 2010/12/31.