(16R,20R)-7β,20-diacetoxy-9-hydroxy-16-methyl-1-oxo-10-phenyl-9,23-seco-[13]cytochalasa-6(12),13t,21t-triene-23-thioic acid S-phenyl ester

Base Information

• Chemical Name: (16R,20R)-7β,20-diacetoxy-9-hydroxy-16-methyl-1-oxo-10-phenyl-9,23-seco-[13]cytochalasa-6(12),13t,21t-triene-23-thioic acid S-phenyl ester
• CAS No.: 64760-39-0
• Molecular Formula: C₃₉H₄₇NO₇S
• Molecular Weight: 673.871
• Mol file: 64760-39-0.mol

Synonyms:(16R,20R)-7β,20-diacetoxy-9-hydroxy-16-methyl-1-oxo-10-phenyl-9,23-seco-[13]cytochalasa-6(12),13t,21t-triene-23-thioic acid S-phenyl ester

Chemical Property of (16R,20R)-7β,20-diacetoxy-9-hydroxy-16-methyl-1-oxo-10-phenyl-9,23-seco-[13]cytochalasa-6(12),13t,21t-triene-23-thioic acid S-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (16R,20R)-7β,20-diacetoxy-9-hydroxy-16-methyl-1-oxo-10-phenyl-9,23-seco-[13]cytochalasa-6(12),13t,21t-triene-23-thioic acid S-phenyl ester

There total 1 articles about (16R,20R)-7β,20-diacetoxy-9-hydroxy-16-methyl-1-oxo-10-phenyl-9,23-seco-[13]cytochalasa-6(12),13t,21t-triene-23-thioic acid S-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (16R,20R)-7β,20-diacetoxy-9-hydroxy-16-methyl-1-oxo-10-phenyl-9,23-seco-[13]cytochalasa-6(12),13t,21t-triene-23-thioic acid S-phenyl ester (64760-39-0)

Guidance literature:

4, 1) wss. Essigsaeure, 2) Acetylierung (S.6758);

DOI:10.1021/ja00462a049

Reference yield:

(16R,20R)-7β,20-diacetoxy-9-hydroxy-16-methyl-1-oxo-10-phenyl-9,23-seco-[13]cytochalasa-6(12),13t,21t-triene-23-thioic acid S-phenyl ester (64760-39-0) → cytochalasin B (14930-96-2)

Guidance literature:

Multi-step reaction with 2 steps

1: Na₂HPO₄, CF₃CO₂Ag / benzene

2: (alkaline hydrolysis)

With disodium hydrogenphosphate; silver trifluoroacetate; In benzene;

DOI:10.1021/ja00462a049

Reference yield:

(16R,20R)-7β,20-diacetoxy-9-hydroxy-16-methyl-1-oxo-10-phenyl-9,23-seco-[13]cytochalasa-6(12),13t,21t-triene-23-thioic acid S-phenyl ester (64760-39-0) → cytochalasin A (14110-64-6)

Guidance literature:

Multi-step reaction with 3 steps

1: Na₂HPO₄, CF₃CO₂Ag / benzene

2: (alkaline hydrolysis)

3: MnO₂

With manganese(IV) oxide; disodium hydrogenphosphate; silver trifluoroacetate; In benzene;

DOI:10.1021/ja00462a049

Downstream raw materials:

7,20-O,O'-di-acetyl-cytochalasin B

7-O-acetyl-cytochalasin B

cytochalasin A

cytochalasin B

Refernces