naphthalen-1-yl-acetic acid benzylidenehydrazide

Base Information

• Chemical Name: naphthalen-1-yl-acetic acid benzylidenehydrazide
• CAS No.: 1094-37-7
• Molecular Formula: C₁₉H₁₆N₂O
• Molecular Weight: 288.349
• Mol file: 1094-37-7.mol

Synonyms:naphthalen-1-yl-acetic acid benzylidenehydrazide

Chemical Property of naphthalen-1-yl-acetic acid benzylidenehydrazide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of naphthalen-1-yl-acetic acid benzylidenehydrazide

There total 4 articles about naphthalen-1-yl-acetic acid benzylidenehydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

naphthalen-1-yl-acetic acid hydrazide (34800-90-3) + benzaldehyde (100-52-7) → naphthalen-1-yl-acetic acid benzylidenehydrazide (1094-37-7)

Guidance literature:

at 83 ℃; for 0.0333333h; microwave irradiation;

Reference yield:

naphth-1-yl acetic acid (86-87-3) → naphthalen-1-yl-acetic acid benzylidenehydrazide (1094-37-7)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. hydrazine hydrate / 4 h / 90 °C

2: 91 percent / 0.03 h / 83 °C / microwave irradiation

With hydrazine hydrate;

Reference yield:

ethyl 2-(1-naphthyl)acetate (2122-70-5) → naphthalen-1-yl-acetic acid benzylidenehydrazide (1094-37-7)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine hydrate / ethanol / 8 h / Reflux

2: ethanol / Reflux

With hydrazine hydrate; In ethanol;

DOI:10.2174/1573406411309020009

upstream raw materials:

naphthalen-1-yl-acetic acid hydrazide

benzaldehyde

naphth-1-yl acetic acid

ethyl 2-(1-naphthyl)acetate

Refernces

• 1、 Li, Jian-Ping,Zheng, Peng-Zhi,Zhu, Jun-Ge,Liu, Rui-Jie,Qu, Gui-Rong. "An expedient method for the synthesis of acylhydrazones under microwave irradiation in solvent-free medium". . p. 90 - 92. Retrieved 2007/10/03.