Technology Process of 1-bromo-11-tert-butyldiphenylsilyloxy-3(Z),6(Z)-undecadiene
There total 5 articles about 1-bromo-11-tert-butyldiphenylsilyloxy-3(Z),6(Z)-undecadiene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
carbon tetrabromide; triphenylphosphine;
In
dichloromethane;
at 0 ℃;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) n-BuLi / 1.) THFm HMPA, hexane, -80 deg C -> -30 deg C, 30 min; -30 deg C, 45 min, 2.) room temperature, 30 h
2: 87 percent / CBr4, Ph3P / CH2Cl2 / 0.75 h
3: 2.) CuCl / 1.) THF, room temperature, 2.5 h, 2.) 40 deg C, 3 h
4: 96 percent / Ni(OAc)4*4H2O, NaBH4, H2, ethylenediamine / aq. ethanol / 4 h
5: 69 percent / CBr4, Ph3P / CH2Cl2 / 0 °C
With
sodium tetrahydroborate; n-butyllithium; carbon tetrabromide; Ni(OAc)4; hydrogen; ethylenediamine; triphenylphosphine; copper(l) chloride;
In
ethanol; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 2.) CuCl / 1.) THF, room temperature, 2.5 h, 2.) 40 deg C, 3 h
2: 96 percent / Ni(OAc)4*4H2O, NaBH4, H2, ethylenediamine / aq. ethanol / 4 h
3: 69 percent / CBr4, Ph3P / CH2Cl2 / 0 °C
With
sodium tetrahydroborate; carbon tetrabromide; Ni(OAc)4; hydrogen; ethylenediamine; triphenylphosphine; copper(l) chloride;
In
ethanol; dichloromethane;