phenyl 4-(hydroxyisopropyl)phenyl ether

Base Information

• Chemical Name: phenyl 4-(hydroxyisopropyl)phenyl ether
• CAS No.: 4974-92-9
• Molecular Formula: C₁₅H₁₆O₂
• Molecular Weight: 228.291
• Mol file: 4974-92-9.mol

Synonyms:phenyl 4-(hydroxyisopropyl)phenyl ether

Chemical Property of phenyl 4-(hydroxyisopropyl)phenyl ether

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phenyl 4-(hydroxyisopropyl)phenyl ether

There total 6 articles about phenyl 4-(hydroxyisopropyl)phenyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-phenoxyacetophenone (5031-78-7) + methylmagnesium bromide (75-16-1) → phenyl 4-(hydroxyisopropyl)phenyl ether (4974-92-9)

Guidance literature:

In diethyl ether; for 3h; Ambient temperature;

DOI:10.1021/jo951414r

Reference yield:

para-bromoacetophenone (99-90-1) → phenyl 4-(hydroxyisopropyl)phenyl ether (4974-92-9)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃ / Cu, CuBr / 200 °C

2: Mg

With potassium carbonate; magnesium; copper; copper(I) bromide;

Reference yield:

phenol (108-95-2,27073-41-2) → phenyl 4-(hydroxyisopropyl)phenyl ether (4974-92-9)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃ / Cu, CuBr / 200 °C

2: Mg

With potassium carbonate; magnesium; copper; copper(I) bromide;

upstream raw materials:

phenyl 4-(chloroisopropyl)phenyl ether

4-phenoxyacetophenone

methyl iodide

methylmagnesium bromide

Downstream raw materials:

phenyl 4-(chloroisopropyl)phenyl ether

Refernces

• 1、 Litvinenko, L. M.,Benndorf, V.,Popova, R. S.,Popov, A. F.,Tormosin, I. I.. "SYNTHESIS AND REACTIVITY OF ARYLOXYCUMENYL CHLORIDES". . p. 680 - 683. Retrieved 2007/10/02.