4-trehalosamine

Base Information

• Chemical Name: 4-trehalosamine
• CAS No.: 51855-99-3
• Molecular Formula: C₁₂H₂₃NO₁₀
• Molecular Weight: 341.315
• Mol file: 51855-99-3.mol

Synonyms:4-Amino-4-deoxy-a,a-trehalose; 4-Trehalosamine

Chemical Property of 4-trehalosamine

Chemical Property:

• Vapor Pressure: 6.45E-21mmHg at 25°C
• Boiling Point: 671.7°Cat760mmHg
• Flash Point: 360°C
• PSA: 195.32000
• Density: 1.7g/cm³
• LogP: -4.73050

Purity/Quality:

4-TREHALOSAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-trehalosamine

There total 22 articles about 4-trehalosamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

4-azido-4-deoxy-α-D-galactopyranosyl α-D-glucopyranoside → 4'-Amino-4'-deoxy-α-D-galactopyranosyl α-D-glucopyranoside (51855-99-3,129785-34-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; for 24h; under 2585.7 Torr; Ambient temperature;

DOI:10.1016/0008-6215(90)84199-5

Reference yield: 80.0%

4-Deoxy-4-trifluoroacetamido-α-D-glucopyranosyl α-D-glucopyranoside (148180-47-6) → 4-amino-4-deoxy-α-D-glucopyranosyl α-D-glucopyranoside (51855-99-3)

Guidance literature:

With Dowex-1*8(OH^(1-)) resin; In ethanol; for 4h; Ambient temperature;

DOI:10.1016/0008-6215(93)84215-R

Reference yield:

4-azido-4-deoxy-α-D-glucopyranosyl α-D-glucopyranoside (129785-35-9) → 4-amino-4-deoxy-α-D-glucopyranosyl α-D-glucopyranoside (51855-99-3)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; for 24h; under 2585.7 Torr; Ambient temperature;

DOI:10.1016/0008-6215(90)84199-5

upstream raw materials:

4-azido-4-deoxy-α-D-glucopyranosyl α-D-glucopyranoside

4-Deoxy-4-trifluoroacetamido-α-D-glucopyranosyl α-D-glucopyranoside

2,3,6-Tri-O-benzoyl-α-D-glucopyranosyl 2,3,4,6-tetra-O-benzoyl-α-D-glucopyranoside

4-Azido-2,3,6-tri-O-benzoyl-4-deoxy-α-D-glucopyranosyl 2,3,4,6-tetra-O-benzoyl-α-D-glucopyranoside

Refernces

• 1、 Rodriguez-Rivera, Frances P.,Zhou, Xiaoxue,Theriot, Julie A.,Bertozzi, Carolyn R.. "Visualization of mycobacterial membrane dynamics in live cells". supporting information. p. 3488 - 3495. Retrieved 2017/03/15.
• 2、 Bassily, Rafik W.,El-Sokkary, Ramadan I.,Silwanis, Basim Azmy,Nematalla, Asaad S.,Nashed, Mina A.. "An improved synthesis of 4-azido-4-deoxy- and 4-amino-4-deoxy-α,α-trehalose and their epimers". . p. 197 - 208. Retrieved 2007/10/02.