Dipropyl malate

Base Information

• Chemical Name: Dipropyl malate
• CAS No.: 6947-10-0
• Molecular Formula: C10H18O5
• Molecular Weight: 218.2469
• NSC Number: 57399
• Mol file: 6947-10-0.mol

Synonyms:Dipropyl malate;Malic acid, dipropyl ester;SCHEMBL2231276;LYTIDDOGVOPTSX-UHFFFAOYSA-N;NSC57399;NSC-57399

Chemical Property of Dipropyl malate

Chemical Property:

• Vapor Pressure: 4.32E-05mmHg at 25°C
• Boiling Point: 313.4°C at 760 mmHg
• Flash Point: 114.3°C
• Density: 1.099g/cm³
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 9
• Exact Mass: 218.11542367
• Heavy Atom Count: 15
• Complexity: 202

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCOC(=O)CC(C(=O)OCCC)O

Technology Process of Dipropyl malate

There total 4 articles about Dipropyl malate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

propan-1-ol (71-23-8) + malic acid (617-48-1,78644-42-5) → dipropyl malate (1587-17-3,6947-10-0)

Guidance literature:

With iron(III) perchlorate; for 3h; Ambient temperature;

DOI:10.1080/00397919208019301

Reference yield:

propan-1-ol (71-23-8) + (S)-Malic acid (97-67-6,78644-42-5) → (S)-(-)-di-n-propyl 2-hydroxybutandioate (145678-47-3,6947-10-0)

Guidance literature:

With hydrogenchloride;

Reference yield:

di-n-propyl 2-oxo-butandioate → (S)-(-)-di-n-propyl 2-hydroxybutandioate (145678-47-3,6947-10-0) + n-propyl 3-hydroxypropionate (4897-95-4) + (R)-di-n-propyl 2-hydroxybutandioate (6947-10-0)

Guidance literature:

With baker's yeast; Title compound not separated from byproducts; Ambient temperature;

DOI:10.1016/S0957-4166(99)00286-4

upstream raw materials:

propan-1-ol

malic acid

(S)-Malic acid

Refernces

• 1、 Drioli, Sara,Nitti, Patrizia,Pitacco, Giuliana,Tossut, Laura,Valentin, Ennio. "Enantiomerically pure tetrahydro-5-oxo-2-furancarboxylic esters from dialkyl 2-oxoglutarates". . p. 2713 - 2728. Retrieved 2007/10/03.