(R)-(1-(2,4,6-Trimethylphenyl)ethyl)amine

Base Information

• Chemical Name: (R)-(1-(2,4,6-Trimethylphenyl)ethyl)amine
• CAS No.: 20050-15-1
• Molecular Formula: C₁₁H₁₇N
• Molecular Weight: 163.263
• Hs Code.: 2921199090
• Mol file: 20050-15-1.mol

Synonyms:Benzenemethanamine,a,2,4,6-tetramethyl-, (R)-;Benzylamine, a,2,4,6-tetramethyl-,(R)-(+)- (8CI);(R)-(1-(2,4,6-Trimethylphenyl)ethyl)amine;

Chemical Property of (R)-(1-(2,4,6-Trimethylphenyl)ethyl)amine

Chemical Property:

• Boiling Point: 254.2 °C at 760 mmHg
• Flash Point: 105.6 °C
• PSA: 26.02000
• Density: 0.93 g/cm³
• LogP: 3.33180

Purity/Quality:

99% ^*data from raw suppliers

(R)-1-Mesitylethanamine 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (R)-(1-(2,4,6-Trimethylphenyl)ethyl)amine

There total 10 articles about (R)-(1-(2,4,6-Trimethylphenyl)ethyl)amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(R)-N-formyl-1-mesitylethylamine → (R)-1-mesitylethylamine (20050-15-1)

Guidance literature:

With hydrogenchloride; In methanol; for 6h; Heating;

DOI:10.1016/S0957-4166(99)00579-0

Reference yield: 90.0%

(S)-N-formyl-1-mesitylethylamine (263351-63-9) → (1S)-1-(2,4,6-trimethylphenyl)ethanamine (20050-17-3,20050-15-1)

Guidance literature:

With hydrogenchloride; In methanol; for 6h; Heating;

DOI:10.1016/S0957-4166(99)00579-0

Reference yield: 88.0%

1-(2,4,6-trimethylphenyl)ethanimine (20173-89-1) → 1-mesitylethylamine (76808-14-5,20050-15-1)

Guidance literature:

With ethanol; ammonia; sodium; In tetrahydrofuran; for 1h; Heating;

DOI:10.1016/S0957-4166(99)00579-0

upstream raw materials:

1-(2,4,6-trimethylphenyl)ethanimine

cyanomesitylene

(S)-N-formyl-1-mesitylethylamine

1-mesitylethylamine

Downstream raw materials:

[(R)-1-(2,4,6-Trimethyl-phenyl)-ethyl]-carbamic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester

[(S)-1-(2,4,6-Trimethyl-phenyl)-ethyl]-carbamic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester

Refernces

• 1、 Kohara, Takehiro,Hashimoto, Yukihiko,Shioya, Rieko,Saigo, Kazuhiko. "A new non-natural chiral auxiliary: Design, synthesis, and resolution of 1-mesitylethylamine and its application in the asymmetric aza-Diels-Alder reaction". . p. 4831 - 4840. Retrieved 2007/10/03.